Joseph J. Eron

TL;DR: The risk of ESRD remains high among HIV-infected individuals in care but is declining with improvements in virologic suppression, coincident with notable increases in both the prevalence of viral suppression and the prevalenceof E SRD risk factors including diabetes mellitus, hypertension, and hepatitis C virus coinfection.

TL;DR: Resistance of HIV to first-line therapy is predictable at 12 months when evaluated by means of HIV RNA monitoring and, when detected, largely preserves second-line Therapy options, critical for long-term prevention of drug resistance.

TL;DR: The data suggest that the presence of HIV- 1-specific CTL activity in HIV-1-infected long-term survivors is an important component in the effective control of HIV -1 replication.

TL;DR: It is suggested that AZT may be useful in drug combination regimens, even when AZT-resistant viruses are isolated in vitro, andixtures of wild-type and mutant reverse transcriptase genes were found in one of the late-AZT therapy isolates.

TL;DR: In this study, CAB LA was well tolerated at the doses and dosing intervals used and was not detectable in plasma both at the time of first reactive HIV test and at the study visit 12 weeks prior to the first reactive test.