J
Joseph J. Eron
Researcher at University of North Carolina at Chapel Hill
Publications - 569
Citations - 49427
Joseph J. Eron is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 99, co-authored 511 publications receiving 44857 citations. Previous affiliations of Joseph J. Eron include Duke University.
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Journal ArticleDOI
Changing prevalence of oral manifestations of human immuno-deficiency virus in the era of protease inhibitor therapy ☆ ☆☆
TL;DR: The pattern of oral opportunistic infections is changing in the era of protease inhibitor use, with some variation by lesion type.
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Selection Bias Due to Loss to Follow Up in Cohort Studies.
TL;DR: This work broadly describes inverse probability-of-censoring weighted estimation and gives a simple example to demonstrate in detail how inverse probabilities mitigates selection bias and describes challenges to estimation.
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Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study
Joseph J. Eron,Bonaventura Clotet,J. Durant,Christine Katlama,Princy Kumar,Adriano Lazzarin,Isabelle Poizot-Martin,Gary Richmond,Vincent Soriano,Mounir Ait-Khaled,Tamio Fujiwara,Jenny Huang,Sherene Min,Cindy Vavro,Jane Yeo +14 more
TL;DR: These data are the first clinical demonstration of the activity of any integrase inhibitor in subjects with HIV-1 resistant to RAL, and dolutegravir 50 mg twice daily with an optimized background provided greater and more durable benefit than the once-daily regimen.
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Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV
Pietro Vernazza,Luigi Troiani,Markus Flepp,Richard W. Cone,Jody Schock,Felix Roth,Katia Boggian,Myron S. Cohen,Susan A. Fiscus,Joseph J. Eron +9 more
TL;DR: In patients with treatment-induced suppression of blood viral load the likelihood of having detectable HIV in semen is very low (< 4%), and seminal shedding of cell-free and cell-associated HIV is significantly lower than in an untreated population of HIV-infected asymptomatic men.
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Novel therapies based on mechanisms of HIV-1 cell entry
J. Michael Kilby,Joseph J. Eron +1 more
TL;DR: The way in which HIV-1 enters cells and potential means of denying the virus admission to cells are reviewed.