Joshua A. Horwitz

TL;DR: Evidence is provided for the generation of partial functional antiviral immune responses against a hepatotropic pathogen in humanized HLA-transgenic mice during a hepatoscopic adenovirus infection.

TL;DR: The data suggest that PEA may be a viable biomaterial for use in tissue engineering applications, particularly for use as a vascular graft.

TL;DR: It is demonstrated that the entire HCV life-cycle can be recapitulated in mouse cells and the barriers of HCV interspecies transmission can be overcome by engineering a suitable cellular environment and provide a blue-print towards constructing a small animal model for HCV infection.

TL;DR: A complete structure of RABV L bound with its phosphoprotein cofactor (P), determined by electron cryo-microscopy at 3.3 Å resolution, shows a conformation poised for initiation of transcription or replication.

TL;DR: A consortium of national gun violence prevention and mental health experts formed to advance an evidence-informed policy agenda on this controversial issue agreed on a guiding principle for future policy recommendations: restricting firearm access on the basis of certain dangerous behaviors is supported by the evidence; restricting access onThe basis of mental illness diagnoses is not.