J
Joshua H. Singer
Researcher at University of Maryland, College Park
Publications - 53
Citations - 3561
Joshua H. Singer is an academic researcher from University of Maryland, College Park. The author has contributed to research in topics: Neurotransmission & Retina. The author has an hindex of 26, co-authored 52 publications receiving 3095 citations. Previous affiliations of Joshua H. Singer include National Institutes of Health & University of Washington.
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Journal ArticleDOI
Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina.
Anu Bansal,Joshua H. Singer,Bryan J. Hwang,Bryan J. Hwang,Wei Xu,A. L. Beaudet,Marla B. Feller +6 more
TL;DR: It is demonstrated here that the neural substrate that generates waves in the mouse retina develops through three distinct stages, and that retinal waves mediated by nAChRs are involved in, but not required for, the development of neural circuits that define the ON and OFF sublamina of the inner plexiform layer.
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Development of Glycinergic Synaptic Transmission to Rat Brain Stem Motoneurons
TL;DR: Glycinergic PSPs are therefore depolarizing and prolonged in neonate HMs and become faster and hyperpolarizing during the first two postnatal weeks.
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Light Affects Mood and Learning through Distinct Retina-Brain Pathways
Diego C. Fernandez,P. Michelle Fogerson,Lorenzo Lazzerini Ospri,Michael B. Thomsen,Robert M. Layne,Daniel Severin,Jesse Zhan,Joshua H. Singer,Alfredo Kirkwood,Haiqing Zhao,David M. Berson,Samer Hattar +11 more
TL;DR: It is revealed that the direct effects of light on learning and mood utilize distinct ipRGC output streams, and the results provide new insights into the neural basis required for light to influence mood and learning.
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DSCAM and DSCAML1 Function in Self-Avoidance in Multiple Cell Types in the Developing Mouse Retina
Peter G. Fuerst,Freyja Bruce,Miao Tian,Wei Wei,Justin Elstrott,Marla B. Feller,Lynda Erskine,Joshua H. Singer,Robert W. Burgess +8 more
TL;DR: DSCAM and DSCAML1 function similarly in self-avoidance, and are not essential for synaptic specificity in the mouse retina.
Journal ArticleDOI
Coordinated multivesicular release at a mammalian ribbon synapse
TL;DR: The release synchrony reflected in these multivesicular events suggests that release within an active zone is coordinated during MVR.