J
Juan A. Squella
Researcher at University of Chile
Publications - 214
Citations - 3431
Juan A. Squella is an academic researcher from University of Chile. The author has contributed to research in topics: Cyclic voltammetry & Nitro. The author has an hindex of 29, co-authored 210 publications receiving 3173 citations. Previous affiliations of Juan A. Squella include Electrochemical Society.
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Trypanosoma cruzi: effect and mode of action of nitroimidazole and nitrofuran derivatives.
Juan Diego Maya,Soledad Bollo,Luis J. Núñez-Vergara,Juan A. Squella,Yolanda Repetto,Antonio Morello,Jacques Périé,G. Chauviere +7 more
TL;DR: The results indicate that nifurtimox and related compounds act as redox cyclers, whereas the most active in the series, the 5-nitroimidazole megazol essentially acts as thiol scavenger particularly for trypanothione, the cofactor for try panothione reductase, an essential enzyme in the detoxification process.
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Antioxidant activity of gallates: an electrochemical study in aqueous media
S. Gunckel,Paola Santander,G. Cordano,Jorge Ferreira,Sergio Muñoz,Luis J. Núñez-Vergara,Juan A. Squella +6 more
TL;DR: From the pH-dependence of the peak current it is possible to affirm that pH 2 is the better condition for the oxidative activity of gallate radicals showing that the antioxidant behaviour of these compounds are important in the stomach acid.
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Recent Developments in the Electrochemistry of Some Nitro Compounds of Biological Significance
TL;DR: The formation of the nitro radical anion as the product of the one electron reduction of nitro compounds generates a series of important consequences passing from chemical to biological aspects as discussed by the authors.
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Electrochemical determination of food colorants in soft drinks using MWCNT-modified GCEs
TL;DR: In this paper, a glassy carbon electrode (GCE) with multi-walled carbon nanotubes (MWCNTs) using 1,3-dioxolane as a dispersant agent, resulting in a stable and reproducible electrochemical sensor was applied to study the food dyes tartrazine, sunset yellow and carmoisine.
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Synthesis and antioxidant study of new polyphenolic hybrid-coumarins
Karina Pérez-Cruz,Mauricio Moncada-Basualto,Mauricio Moncada-Basualto,Javier Morales-Valenzuela,Germán Barriga-González,P.A. Navarrete-Encina,L. J. Nuñez-Vergara,Juan A. Squella,Claudio Olea-Azar +8 more
TL;DR: In this paper, the antioxidant capacity of hydroxylated coumarins and hydroxybenzoic acids was evaluated against reactive oxygen species (ROS) using oxygen radical absorbance capacity-fluorescein (ORAC-FL), electron spin resonance (ESR) spin trapping, quenching of superoxide anion, cellular antioxidant activity (CAA), and a ferric reducing ability of plasma (FRAP assay).