J
Junjie Xiao
Researcher at Shanghai University
Publications - 206
Citations - 6196
Junjie Xiao is an academic researcher from Shanghai University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 39, co-authored 154 publications receiving 4451 citations. Previous affiliations of Junjie Xiao include Chinese Ministry of Education & Tongji University.
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Journal ArticleDOI
Circular RNAs: Promising Biomarkers for Human Diseases.
TL;DR: The current understanding of biogenesis and gene regulatory mechanisms of circRNAs is provided, the recent studies oncircRNAs as potential diagnostic and prognostic biomarkers are summarized, and the major advantages and limitations of circ RNAs as novel biomarkers based on existing knowledge are highlighted.
Journal ArticleDOI
miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling
Xiaojun Liu,Junjie Xiao,Han Zhu,Xin Wei,Colin Platt,Federico Damilano,Chunyang Xiao,Vassilios J. Bezzerides,Vassilios J. Bezzerides,Pontus Boström,Lin Che,Chunxiang Zhang,Bruce M. Spiegelman,Anthony Rosenzweig,Anthony Rosenzweig +14 more
TL;DR: In this article, microRNA-222 (miR-222) was upregulated in two distinct models of exercise and found that it was sufficient to protect the heart against adverse remodeling.
Journal ArticleDOI
Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome
Yanzong Yang,Yiqing Yang,Bo Liang,Bo Liang,Jinqiu Liu,Jun Li,Morten Grunnet,Morten Grunnet,Søren-Peter Olesen,Søren-Peter Olesen,Hanne B. Rasmussen,Hanne B. Rasmussen,Patrick T. Ellinor,Lianjun Gao,Xiaoping Lin,Li Li,Lei Wang,Junjie Xiao,Yi Liu,Ying Liu,Shulong Zhang,Dandan Liang,Luying Peng,Thomas Jespersen,Thomas Jespersen,Yi-Han Chen +25 more
TL;DR: The findings suggest a role for Kir3.4 in the etiology of LQTS, a hereditary disorder that leads to sudden cardiac death secondary to fatal cardiac arrhythmias in a large Chinese family with autosomal-dominant LQ TS.
Journal ArticleDOI
miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury.
Jing Shi,Yihua Bei,Xiangqing Kong,Xiaojun Liu,Zhiyong Lei,Tianzhao Xu,Hui Wang,Qinkao Xuan,Ping Chen,Jiahong Xu,Lin Che,Hui Liu,Jiuchang Zhong,Joost P.G. Sluijter,Xinli Li,Anthony Rosenzweig,Junjie Xiao +16 more
TL;DR: It is suggested that miR-17-3p contributes to exercise-induced cardiac growth and protects against adverse ventricular remodeling and may represent a novel therapeutic target to promote functional recovery after cardiac ischemia/reperfusion.
Journal ArticleDOI
miR-29b contributes to multiple types of muscle atrophy.
Jin Li,Mun Chun Chan,Yan Yu,Yihua Bei,Ping Chen,Qiulian Zhou,Liming Cheng,Lei Chen,Olivia Ziegler,Glenn C. Rowe,Saumya Das,Junjie Xiao +11 more
TL;DR: It is suggested that miR-29b contributes to multiple types of muscle atrophy via targeting of IGF-1 and PI3K(p85α) and that suppression of miR -29b may represent a therapeutic approach for muscle atrophia induced by different stimuli.