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Saumya Das

Researcher at Harvard University

Publications -  195
Citations -  14335

Saumya Das is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Heart failure. The author has an hindex of 42, co-authored 150 publications receiving 9627 citations. Previous affiliations of Saumya Das include Beth Israel Deaconess Medical Center & Centro Nacional de Investigaciones Cardiovasculares.

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Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, +417 more
TL;DR: The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities, and a checklist is provided with summaries of key points.
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Amyloid-associated proteins α 1 -antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

TL;DR: It is reported that α,anti-chymotrypsin or apoE to the Aβ peptide promoted a 10- to 20-fold increase in filament formation, with apOE-4, the isoform recently linked to the development of late-onset Alzheimer's disease, showing the highest catalytic activity.
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Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A.

TL;DR: The characterization of a regulatory NMDAR subunit, NR3A, is reported, which is expressed primarily during brain development and suggested to be involved in the development of synaptic elements by modulating N MDAR activity.
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Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper

TL;DR: This position paper was written by the participants of the workshop to give an overview of the current state of knowledge in the field and to clarify that incomplete knowledge – of the nature of EV(-RNA)s and of how to effectively and reliably study them – currently prohibits the implementation of gold standards in EV-RNA research.
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Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation.

TL;DR: CPAP is an important therapy in OSA patients undergoing PVI that improves arrhythmia free survival and PVI offers limited value to OSA Patients not treated with CPAP.