J
Justo Cobo
Researcher at University of Jaén
Publications - 492
Citations - 3545
Justo Cobo is an academic researcher from University of Jaén. The author has contributed to research in topics: Hydrogen bond & Molecule. The author has an hindex of 26, co-authored 484 publications receiving 3148 citations.
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Journal ArticleDOI
7-Amino-5-methyl-2-phenyl-6-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine crystallizes with Z′ = 2: pseudosymmetry and the formation of complex sheets built from N—H⋯N and C—H⋯π(arene) hydrogen bonds
TL;DR: The title compound, C(19)H(16)N(6), crystallizes with Z' = 2 in the space group P2(1)/n and is linked into complex sheets by a combination of two intermolecular N-H…N and four C-H...pi(arene) hydrogen bonds.
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A π-stacked chain of hydrogen-bonded dimers in 3-tert-butyl-1-(4-chlorophenyl)-4-phenylindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-one and a π-stacked sheet of hydrogen-bonded chains in 3-tert-butyl-1-(4-chlorophenyl)-4-(4-methoxyphenyl)indeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-one.
TL;DR: In 3-tert-butyl-1-(4-chlorophenyl)-4-phenylindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-one, a combination of C-H···O and C- H···π(arene) hydrogen bonds links the molecules into chains of rings, which are further linked into sheets by a π-π stacking interaction.
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7-Amino-2-tert-butyl-5-methylpyrazolo[1,5-a]pyrimidine: a three-dimensional framework structure built from two N—H⋯N hydrogen bonds
TL;DR: The bond distances in the title compound, C11H16N4, provide evidence for peripheral delocalization of pi electrons.
Journal ArticleDOI
Efficient Microwave-Assisted Synthesis and Antitumor Activity of Novel 4,4′-Methylenebis[2-(3-aryl-4,5-dihydro-1H-pyrazol-5-yl)phenols].
Braulio Insuasty,Angélica García,Jairo Quiroga,Rodrigo Abonia,Alejandro Ortiz,Manuel Nogueras,Justo Cobo +6 more
TL;DR: In this article, a series of title bis(diarylpyrazoline) derivatives are synthesized by microwave-assisted cyclocondensation of methylene-bischalcones (I) with hydrazine hydrate.
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Hypothalamic and plasmatic angiotensin metabolism in L-NAME treated rats.
Ana Belén Segarra,M. Ramírez,Ana Belén Villarejo,Inmaculada Banegas,Francisco Vives,M. de Gasparo,Francisco Alba,Justo Cobo,Isabel Prieto +8 more
TL;DR: Results suggested mainly a higher formation of Ang III, but also higher levels of Ang IV in the hypothalamus of L-NAME treated rats, which may counteract the hypertensive action of Ang II at the periphery.