K
Karin Nielsen-Saines
Researcher at University of California, Los Angeles
Publications - 179
Citations - 13260
Karin Nielsen-Saines is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Medicine & Pregnancy. The author has an hindex of 30, co-authored 137 publications receiving 11361 citations.
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Journal ArticleDOI
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Myron S. Cohen,Ying Q. Chen,Marybeth McCauley,Theresa Gamble,Mina C. Hosseinipour,Nagalingeswaran Kumarasamy,James Hakim,Johnstone Kumwenda,Beatriz Grinsztejn,José Henrique Pilotto,Sheela Godbole,Sanjay Mehendale,Suwat Chariyalertsak,Breno Santos,Kenneth H. Mayer,Irving F. Hoffman,Susan H. Eshleman,Estelle Piwowar-Manning,Lei Wang,Joseph Makhema,Lisa A. Mills,Guy de Bruyn,Ian Sanne,Joseph J. Eron,Joel E. Gallant,Diane V. Havlir,Susan Swindells,Heather J. Ribaudo,Vanessa Elharrar,David N. Burns,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Myron Essex,Thomas R. Fleming +34 more
TL;DR: In this article, Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.
Journal ArticleDOI
Zika Virus Infection in Pregnant Women in Rio de Janeiro - Preliminary Report.
Abstr Act,Patrícia Brasil,Jose Paulo Pereira,Claudia Raja Gabaglia,Luana Damasceno,Mayumi Duarte Wakimoto,Rita Maria Ribeiro Nogueira,Patricia Carvalho de Sequeira,André M. Siqueira,Liege Maria Abreu de Carvalho,Denise Cotrim da Cunha,Guilherme Amaral Calvet,Elizabeth de Souza Neves,Maria Elisabeth Lopes Moreira,Ana Elisa Rodrigues Baião,Paulo Roberto Nassar de Carvalho,Carla Janzen,Stephanie G. Valderramos,James D. Cherry,Ana Maria Bispo de Filippis,Karin Nielsen-Saines +20 more
TL;DR: Despite mild clinical symptoms in the mother, ZIKV infection during pregnancy is deleterious to the fetus and is associated with fetal death, fetal growth restriction, and a spectrum of central nervous system abnormalities.
Journal ArticleDOI
Real estimates of mortality following COVID-19 infection.
TL;DR: This poster presents a poster presented at the 2016 International Conference of the Association for the Advance Study of Childbirth and Materno-fetal and Obstetrics entitled “Advances in Maternity and Childbirth Education and Research: Foundations of Pediatric Infectious Diseases.”
Journal ArticleDOI
Zika Virus Infection in Pregnant Women in Rio de Janeiro—Preliminary Report
Patrícia Brasil,Jose Paulo Pereira,Claudia Raja Gabaglia,Luana Damasceno,Mayumi Duarte Wakimoto,Rita Maria Ribeiro Nogueira,Patricia Carvalho de Sequeira,André M. Siqueira,Liege Maria Abreu de Carvalho,Denise Cotrim da Cunha,Guilherme Amaral Calvet,Elizabeth de Souza Neves,Maria Elisabeth Lopes Moreira,Ana Elisa Rodrigues Baião,Paulo Roberto Nassar de Carvalho,Carla Janzen,Stephanie G. Valderramos,James D. Cherry,Ana Maria Bispo de Filippis,Karin Nielsen-Saines +19 more
TL;DR: ZIKV was first identified in Brazil in 2015 by reverse transcriptase–polymerase chain reaction assays of serum specimens from patients who presented with a dengue-like illness that was characterized by rash, fever, myalgias, arthralgias, and conjunctivitis.
Journal ArticleDOI
Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial
Beatriz Grinsztejn,Mina C. Hosseinipour,Heather J. Ribaudo,Susan Swindells,Joseph J. Eron,Ying Q. Chen,Lei Wang,San San Ou,Maija Anderson,Marybeth McCauley,Theresa Gamble,N. Kumarasamy,James Hakim,Johnstone Kumwenda,José Henrique Pilotto,Sheela Godbole,Suwat Chariyalertsak,Marineide Gonçalves de Melo,Kenneth H. Mayer,Susan H. Eshleman,Estelle Piwowar-Manning,Joseph Makhema,Lisa A. Mills,Ravindre Panchia,Ian Sanne,Joel E. Gallant,Irving F. Hoffman,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Max Essex,Diane V. Havlir,Myron S. Cohen +32 more
TL;DR: The clinical benefits recorded, combined with the striking reduction in HIV-1 transmission risk previously reported, provides strong support for earlier initiation of antiretroviral treatment.