Karsten Schnatbaum

TL;DR: A mass-spectrometry-based draft of the human proteome and a public, high-performance, in-memory database for real-time analysis of terabytes of big data, called ProteomicsDB are presented, which enables navigation of proteomes, provides biological insight and fosters the development of proteomic technology.

TL;DR: A deep learning–based tool, Prosit, predicts high-quality peptide tandem mass spectra, improving peptide-identification performance compared with that of traditional proteomics analysis methods.

TL;DR: A quantitative proteome and transcriptome abundance atlas of 29 paired healthy human tissues from the Human Protein Atlas project revealed that hundreds of proteins, particularly in testis, could not be detected even for highly expressed mRNAs and that protein expression is often more stable across tissues than that of transcripts.

TL;DR: ProteomeTools, a project building molecular and digital tools from the human proteome to facilitate biomedical research, is described and the generation and multimodal liquid chromatography–tandem mass spectrometry analysis of >330,000 synthetic tryptic peptides representing essentially all canonical human gene products is reported.

TL;DR: In this article, the functional relevance of preexisting cross-immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a subject of intense debate.