S
Shyamalika Gopalan
Researcher at Stony Brook University
Publications - 18
Citations - 842
Shyamalika Gopalan is an academic researcher from Stony Brook University. The author has contributed to research in topics: Population & Biology. The author has an hindex of 7, co-authored 15 publications receiving 603 citations. Previous affiliations of Shyamalika Gopalan include McGill University & University of Southern California.
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Journal ArticleDOI
Early farmers from across Europe directly descended from Neolithic Aegeans
Zuzana Hofmanová,Susanne Kreutzer,Garrett Hellenthal,Christian Sell,Yoan Diekmann,David Díez-del-Molino,Lucy van Dorp,Saioa López,Athanasios Kousathanas,Athanasios Kousathanas,Vivian Link,Vivian Link,Karola Kirsanow,Lara M. Cassidy,Rui Martiniano,Melanie Strobel,Amelie Scheu,Amelie Scheu,Kostas Kotsakis,Paul Halstead,Sevi Triantaphyllou,Nina Kyparissi-Apostolika,Dushka Urem-Kotsou,Christina Ziota,Fotini Adaktylou,Shyamalika Gopalan,Dean Bobo,Laura Winkelbach,Jens Blöcher,Martina Unterländer,Christoph Leuenberger,Çiler Çilingiroğlu,Barbara Horejs,Fokke Gerritsen,Stephen Shennan,Daniel G. Bradley,Mathias Currat,Krishna R. Veeramah,Daniel Wegmann,Daniel Wegmann,Mark G. Thomas,Christina Papageorgopoulou,Joachim Burger +42 more
TL;DR: This study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.
Journal ArticleDOI
Ancient European dog genomes reveal continuity since the Early Neolithic.
Laura R. Botigué,Shiya Song,Amelie Scheu,Shyamalika Gopalan,Amanda L. Pendleton,Matthew T. Oetjens,Angela M. Taravella,Timo Seregély,Andrea Zeeb-Lanz,Rose-Marie Arbogast,Dean Bobo,Kevin G. Daly,Martina Unterländer,Joachim Burger,Jeffrey M. Kidd,Krishna R. Veeramah +15 more
TL;DR: The genomes of an Early and End Neolithic dog from Germany demonstrate continuity with each other and predominantly share ancestry with modern European dogs, contradicting a previously suggested Late Neolithic population replacement.
Journal ArticleDOI
Trends in DNA Methylation with Age Replicate Across Diverse Human Populations
Shyamalika Gopalan,Oana Carja,Maud Fagny,Etienne Patin,Etienne Patin,Justin W Myrick,Lisa M. McEwen,Sarah M Mah,Michael S. Kobor,Alain Froment,Alain Froment,Marcus W. Feldman,Lluis Quintana-Murci,Lluis Quintana-Murci,Brenna M. Henn +14 more
TL;DR: It is confirmed that an age-associated site in the promoter of the gene ELOVL2 shows a remarkably congruent relationship with aging in humans, despite extensive genetic and environmental variation across populations, and it is demonstrated that genotype state at methylation quantitative trait loci (meQTLs) can affect methylation trends at some age- associated CpG sites.
Journal ArticleDOI
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization.
Gita A. Pathak,Gita A. Pathak,Kritika Singh,Tyne W Miller-Fleming,Frank R. Wendt,Frank R. Wendt,Nava Ehsan,Kangcheng Hou,Ruth Johnson,Zeyun Lu,Shyamalika Gopalan,Loic Yengo,Pejman Mohammadi,Bogdan Pasaniuc,Renato Polimanti,Renato Polimanti,Lea K. Davis,Nicholas Mancuso +17 more
TL;DR: In this paper, the authors integrated a genome-wide association study of COVID-19 hospitalization with mRNA expression, splicing, and protein levels (n = 18,502).
Posted ContentDOI
Early farmers from across Europe directly descended from Neolithic Aegeans
Zuzana Hofmanová,Susanne Kreutzer,Garrett Hellenthal,Christian Sell,Yoan Diekmann,David Díez-del-Molino,Lucy van Dorp,Saioa López,Athanasios Kousathanas,Vivian Link,Karola Kirsanow,Lara M. Cassidy,Rui Martiniano,Melanie Strobel,Amelie Scheu,Kostas Kotsakis,Paul Halstead,Sevi Triantaphyllou,Nina Kyparissi-Apostolika,Dushanka-Christina Urem-Kotsou,Christina Ziota,Fotini Adaktylou,Shyamalika Gopalan,Dean Bobo,Laura Winkelbach,Jens Blöcher,Martina Unterländer,Christoph Leuenberger,Çiler Çilingiroğlu,Barbara Horejs,Fokke Gerritsen,Stephen Shennan,Daniel G. Bradley,Mathias Currat,Krishna R. Veeramah,Daniel Wegmann,Mark G. Thomas,Christina Papageorgopoulou,Joachim Burger +38 more
TL;DR: This study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.