Colin A. Hodgkinson

TL;DR: Using a transgenic insertional mutation at this locus, a gene whose expression is disrupted in transgenic animals is identified and encodes a novel member of the basic-helix-loop-helIX-leucine zipper (bHLH-ZIP) protein family of transcription factors.

TL;DR: It is shown that Mi protein binds DNA as a homo- or heterodimer with TFEB, TFE3, or TFEC, together constituting a new MiT family, suggesting that Mi's critical roles in melanocyte survival and pigmentation are mediated by MiTFamily interactions and transcriptional activities.

TL;DR: The molecular defects associated with eight murine mi mutations are characterized, which vary in both their mode of inheritance and in the cell types they affect.

TL;DR: Data from a case-control study of a North American white population confirms the underrepresentation of a common haplotype of the intron 1/exon 2 region in individuals with schizoaffective disorder and supports the idea that these apparently distinct disorders have at least a partially convergent etiology and that variation at the DISC1 locus predisposes individuals to a variety of psychiatric disorders.

TL;DR: The largest genome-wide association study to date of DSM-IV-diagnosed AD found loci associated with AD and characterized the relationship between AD and other psychiatric and behavioral outcomes, underscoring the genetic distinction between pathological and nonpathological drinking behaviors.