K
Kenji Nakahigashi
Researcher at Keio University
Publications - 54
Citations - 4194
Kenji Nakahigashi is an academic researcher from Keio University. The author has contributed to research in topics: Mutant & Escherichia coli. The author has an hindex of 29, co-authored 54 publications receiving 3920 citations. Previous affiliations of Kenji Nakahigashi include Kyoto University & National University of Singapore.
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Journal ArticleDOI
Multiple high-throughput analyses monitor the response of E. coli to perturbations.
Nobuyoshi Ishii,Kenji Nakahigashi,Tomoya Baba,Tomoya Baba,Martin Robert,Tomoyoshi Soga,Akio Kanai,Takashi Hirasawa,Miki Naba,Kenta Hirai,Aminul Hoque,Pei Yee Ho,Yuji Kakazu,Kaori Sugawara,Saori Igarashi,Satoshi Harada,Takeshi Masuda,Naoyuki Sugiyama,Takashi Togashi,Miki Hasegawa,Yuki Takai,Katsuyuki Yugi,Kazuharu Arakawa,Nayuta Iwata,Yoshihiro Toya,Yoichi Nakayama,Takaaki Nishioka,Takaaki Nishioka,Kazuyuki Shimizu,Kazuyuki Shimizu,Hirotada Mori,Hirotada Mori,Masaru Tomita +32 more
TL;DR: E. coli seems to use complementary strategies that result in a metabolic network robust against perturbations, and actively regulated enzyme levels to maintain a stable metabolic state in response to changes in growth rate.
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Large-scale identification of protein-protein interaction of Escherichia coli K-12.
Mohammad Arifuzzaman,Maki Maeda,Aya Itoh,Kensaku Nishikata,Chiharu Takita,Rintaro Saito,Takeshi Ara,Kenji Nakahigashi,Hsuan Cheng Huang,Aki Hirai,Kohei Tsuzuki,Seira Nakamura,Mohammad Altaf-Ul-Amin,Taku Oshima,Tomoya Baba,Tomoya Baba,Natsuko Yamamoto,Tomoyo Kawamura,Tomoko Ioka-Nakamichi,Masanari Kitagawa,Masaru Tomita,Shigehiko Kanaya,Chieko Wada,Hirotada Mori,Hirotada Mori +24 more
TL;DR: An extended analysis of these interacting networks by bioinformatics and experimentation should provide new insights and novel strategies for E. coli systems biology.
Journal ArticleDOI
Regulation of the heat-shock response.
Takashi Yura,Kenji Nakahigashi +1 more
TL;DR: Current models of both heat induction and the chaperone-mediated feedback control of the sigma32 regulon in Escherichia coli have been further substantiated, and the extent of conservation among Gram-negative bacteria has been assessed.
Journal ArticleDOI
Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1
Sibum Sung,Yuehui He,Yuehui He,Tifani W Eshoo,Yosuke Tamada,Lianna M. Johnson,Kenji Nakahigashi,Koji Goto,Steve E. Jacobsen,Richard M. Amasino +9 more
TL;DR: It is reported that A. thaliana LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) is necessary to maintain the epigenetically repressed state of FLC upon return to warm conditions typical of spring.
Journal ArticleDOI
Update on the Keio collection of Escherichia coli single‐gene deletion mutants
Natsuko Yamamoto,Kenji Nakahigashi,Tomoko Nakamichi,Mihoko Yoshino,Yuki Takai,Yae Touda,Akemi Furubayashi,Satoko Kinjyo,Hitomi Dose,Miki Hasegawa,Kirill A. Datsenko,Toru Nakayashiki,Masaru Tomita,Barry L. Wanner,Hirotada Mori,Hirotada Mori +15 more
TL;DR: The Keio collection has been established as a set of single‐gene deletion mutants of Escherichia coli K‐12 that have a precisely designed deletion from the second codon from the seventh to the last codon of each predicted ORF.