T
Takaaki Nishioka
Researcher at Kyoto University
Publications - 160
Citations - 12496
Takaaki Nishioka is an academic researcher from Kyoto University. The author has contributed to research in topics: Glutathione synthetase & Lipase. The author has an hindex of 47, co-authored 160 publications receiving 11564 citations. Previous affiliations of Takaaki Nishioka include Keio University.
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MassBank: a public repository for sharing mass spectral data for life sciences.
Hisayuki Horai,Masanori Arita,Masanori Arita,Shigehiko Kanaya,Yoshito Nihei,Tasuku Ikeda,Kazuhiro Suwa,Yuya Ojima,Kenichi Tanaka,Satoshi Tanaka,Ken Aoshima,Yoshiya Oda,Yuji Kakazu,Miyako Kusano,Takayuki Tohge,Fumio Matsuda,Yuji Sawada,Masami Yokota Hirai,Hiroki Nakanishi,Kazutaka Ikeda,Naoshige Akimoto,Takashi Maoka,Hiroki Takahashi,Takeshi Ara,Nozomu Sakurai,Hideyuki Suzuki,Daisuke Shibata,Steffen Neumann,Takashi Iida,Ken Tanaka,Kimito Funatsu,Fumito Matsuura,Tomoyoshi Soga,Ryo Taguchi,Kazuki Saito,Takaaki Nishioka +35 more
TL;DR: MassBank is the first public repository of mass spectra of small chemical compounds for life sciences and provides a merged spectrum for each compound prepared by merging the analyzed ESI-MS(2) data on an identical compound under different collision-induced dissociation conditions.
Journal ArticleDOI
Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry
TL;DR: A new approach for the comprehensive and quantitative analysis of charged metabolites by capillary electrophoresis mass spectrometry (CE-MS) is proposed, which enabled the determination of 352 metabolic standards and its utility was demonstrated in the analysis of 1692 metabolites from Bacillus subtilis extracts.
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Multiple high-throughput analyses monitor the response of E. coli to perturbations.
Nobuyoshi Ishii,Kenji Nakahigashi,Tomoya Baba,Tomoya Baba,Martin Robert,Tomoyoshi Soga,Akio Kanai,Takashi Hirasawa,Miki Naba,Kenta Hirai,Aminul Hoque,Pei Yee Ho,Yuji Kakazu,Kaori Sugawara,Saori Igarashi,Satoshi Harada,Takeshi Masuda,Naoyuki Sugiyama,Takashi Togashi,Miki Hasegawa,Yuki Takai,Katsuyuki Yugi,Kazuharu Arakawa,Nayuta Iwata,Yoshihiro Toya,Yoichi Nakayama,Takaaki Nishioka,Takaaki Nishioka,Kazuyuki Shimizu,Kazuyuki Shimizu,Hirotada Mori,Hirotada Mori,Masaru Tomita +32 more
TL;DR: E. coli seems to use complementary strategies that result in a metabolic network robust against perturbations, and actively regulated enzyme levels to maintain a stable metabolic state in response to changes in growth rate.
Journal ArticleDOI
Herbivory-induced volatiles elicit defence genes in lima bean leaves.
Gen Ichiro Arimura,Rika Ozawa,Takeshi Shimoda,Takaaki Nishioka,Wilhelm Boland,Junji Takabayashi +5 more
TL;DR: It is shown that uninfested lima bean leaves activate five separate defence genes when exposed to volatiles from conspecific leaves infested with T. urticae, but not when exposed with volatile from artificially wounded leaves.
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Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption.
Tomoyoshi Soga,Richard Baran,Makoto Suematsu,Yuki Ueno,Satsuki Ikeda,Tadayuki Sakurakawa,Yuji Kakazu,Takamasa Ishikawa,Martin Robert,Takaaki Nishioka,Masaru Tomita +10 more
TL;DR: A metabolome differential display method based on capillary electrophoresis time-of-flight mass spectrometry to profile liver metabolites following acetaminophen-induced hepatotoxicity finds that serum ophthalmate is a sensitive indicator of hepatic GSH depletion, and may be a new biomarker for oxidative stress.