T
Tomoyoshi Soga
Researcher at Keio University
Publications - 432
Citations - 26045
Tomoyoshi Soga is an academic researcher from Keio University. The author has contributed to research in topics: Metabolome & Capillary electrophoresis. The author has an hindex of 71, co-authored 392 publications receiving 21209 citations. Previous affiliations of Tomoyoshi Soga include Agilent Technologies & Ajinomoto.
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Journal ArticleDOI
MassBank: a public repository for sharing mass spectral data for life sciences.
Hisayuki Horai,Masanori Arita,Masanori Arita,Shigehiko Kanaya,Yoshito Nihei,Tasuku Ikeda,Kazuhiro Suwa,Yuya Ojima,Kenichi Tanaka,Satoshi Tanaka,Ken Aoshima,Yoshiya Oda,Yuji Kakazu,Miyako Kusano,Takayuki Tohge,Fumio Matsuda,Yuji Sawada,Masami Yokota Hirai,Hiroki Nakanishi,Kazutaka Ikeda,Naoshige Akimoto,Takashi Maoka,Hiroki Takahashi,Takeshi Ara,Nozomu Sakurai,Hideyuki Suzuki,Daisuke Shibata,Steffen Neumann,Takashi Iida,Ken Tanaka,Kimito Funatsu,Fumito Matsuura,Tomoyoshi Soga,Ryo Taguchi,Kazuki Saito,Takaaki Nishioka +35 more
TL;DR: MassBank is the first public repository of mass spectra of small chemical compounds for life sciences and provides a merged spectrum for each compound prepared by merging the analyzed ESI-MS(2) data on an identical compound under different collision-induced dissociation conditions.
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Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry
TL;DR: A new approach for the comprehensive and quantitative analysis of charged metabolites by capillary electrophoresis mass spectrometry (CE-MS) is proposed, which enabled the determination of 352 metabolic standards and its utility was demonstrated in the analysis of 1692 metabolites from Bacillus subtilis extracts.
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Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry
Akiyoshi Hirayama,Kenjiro Kami,Masahiro Sugimoto,Maki Sugawara,Naoko Toki,Hiroko Onozuka,Taira Kinoshita,Norio Saito,Atsushi Ochiai,Masaru Tomita,Hiroyasu Esumi,Tomoyoshi Soga +11 more
TL;DR: Capillary electrophoresis coupled to mass spectrometry-based metabolomics, which is capable of quantifying the levels of energy metabolites in tissues, could be a powerful tool for the development of novel anticancer agents that target cancer-specific metabolism.
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Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles
Masahiro Sugimoto,David T.W. Wong,David T.W. Wong,Akiyoshi Hirayama,Tomoyoshi Soga,Masaru Tomita +5 more
TL;DR: A comprehensive metabolite analysis of saliva samples obtained from 215 individuals using capillary electrophoresis time-of-flight mass spectrometry identified 57 principal metabolites that can be used to accurately predict the probability of being affected by each individual disease.
Journal ArticleDOI
Multiple high-throughput analyses monitor the response of E. coli to perturbations.
Nobuyoshi Ishii,Kenji Nakahigashi,Tomoya Baba,Tomoya Baba,Martin Robert,Tomoyoshi Soga,Akio Kanai,Takashi Hirasawa,Miki Naba,Kenta Hirai,Aminul Hoque,Pei Yee Ho,Yuji Kakazu,Kaori Sugawara,Saori Igarashi,Satoshi Harada,Takeshi Masuda,Naoyuki Sugiyama,Takashi Togashi,Miki Hasegawa,Yuki Takai,Katsuyuki Yugi,Kazuharu Arakawa,Nayuta Iwata,Yoshihiro Toya,Yoichi Nakayama,Takaaki Nishioka,Takaaki Nishioka,Kazuyuki Shimizu,Kazuyuki Shimizu,Hirotada Mori,Hirotada Mori,Masaru Tomita +32 more
TL;DR: E. coli seems to use complementary strategies that result in a metabolic network robust against perturbations, and actively regulated enzyme levels to maintain a stable metabolic state in response to changes in growth rate.