K
Kevin Huynh
Researcher at Baker IDI Heart and Diabetes Institute
Publications - 88
Citations - 1964
Kevin Huynh is an academic researcher from Baker IDI Heart and Diabetes Institute. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 65 publications receiving 1031 citations. Previous affiliations of Kevin Huynh include Monash University, Clayton campus & California NanoSystems Institute.
Papers
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Journal ArticleDOI
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors.
Kevin Huynh,Christopher K. Barlow,Kaushala S. Jayawardana,Jacquelyn M. Weir,Natalie A. Mellett,Michelle Cinel,Dianna J. Magliano,Jonathan E. Shaw,Brian G. Drew,Peter J. Meikle,Peter J. Meikle +10 more
TL;DR: A chromatography gradient coupled with a detailed characterization of the human plasma lipidome is reported to provide improved resolution and identification of 636 lipid species, including previously unreported species, in a 15-min analysis.
Journal ArticleDOI
Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.
Mika Hilvo,Peter J. Meikle,Peter J. Meikle,Eva Ringdal Pedersen,Grethe S. Tell,Indu Dhar,Hermann Brenner,Hermann Brenner,Ben Schöttker,Ben Schöttker,Mitja Lääperi,Dimple Kauhanen,Kaisa M. Koistinen,Antti Jylhä,Kevin Huynh,Natalie A. Mellett,Andrew Tonkin,David R. Sullivan,John Simes,Paul J. Nestel,Wolfgang Koenig,Wolfgang Koenig,Dietrich Rothenbacher,Dietrich Rothenbacher,Ottar Nygård,Ottar Nygård,Reijo Laaksonen +26 more
TL;DR: The ceramide-phospholipid risk score showed comparable and synergistic predictive performance with previously published CVD risk models for secondary prevention and can efficiently predict residual CVD event risk in patients with coronary artery disease.
Journal ArticleDOI
Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression
Kang-Yu Peng,Kang-Yu Peng,Matthew J. Watt,Sander S. Rensen,Jan Greve,Kevin Huynh,Kaushala S. Jayawardana,Peter J. Meikle,Peter J. Meikle,Ruth C. R. Meex +9 more
TL;DR: It is proposed that increased levels of cardiolipin and ubiquinone may help to preserve mitochondrial function in early NAFLD, but that mitochondrial function eventually fails with progression to NASH, leading to increased acylcarnitine.
Journal ArticleDOI
Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome.
Matthias Arnold,Kwangsik Nho,Alexandra Kueider-Paisley,Tyler Massaro,Kevin Huynh,Barbara Brauner,Siamak MahmoudianDehkordi,Gregory Louie,M. Arthur Moseley,J. Will Thompson,Lisa St John Williams,Jessica D. Tenenbaum,Colette Blach,Rui Chang,Roberta Diaz Brinton,Rebecca Baillie,Xianlin Han,John Q. Trojanowski,Leslie M. Shaw,Ralph N. Martins,Ralph N. Martins,Michael W. Weiner,Eugenia Trushina,Jon B. Toledo,Jon B. Toledo,Peter J. Meikle,David A. Bennett,Jan Krumsiek,P. Murali Doraiswamy,Andrew J. Saykin,Rima Kaddurah-Daouk,Gabi Kastenmüller +31 more
TL;DR: How sex and APOE ε4 genotype modify the association between Alzheimer’s disease biomarkers and metabolites in serum is investigated to suggest that females experience greater impairment of mitochondrial energy production than males.
Journal ArticleDOI
Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention
Piyushkumar A. Mundra,Christopher K. Barlow,Paul J. Nestel,Elizabeth H Barnes,Adrienne Kirby,Peter L. Thompson,David R. Sullivan,Zahir H Alshehry,Zahir H Alshehry,Natalie A. Mellett,Kevin Huynh,Kaushala S. Jayawardana,Corey Giles,Malcolm J. McConville,Sophia Zoungas,Sophia Zoungas,Graham S. Hillis,Graham S. Hillis,John Chalmers,Mark Woodward,Gerard Wong,Bronwyn A. Kingwell,John Simes,Andrew Tonkin,Peter J. Meikle,Lipid Study Investigators +25 more
TL;DR: The improvement in the prediction of cardiovascular outcomes, above conventional risk factors, demonstrates the potential of plasma lipidomic profiles as biomarkers for cardiovascular risk stratification in secondary prevention.