K
Kil Sun Lee
Researcher at Federal University of São Paulo
Publications - 46
Citations - 2275
Kil Sun Lee is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Sleep deprivation & Skeletal muscle. The author has an hindex of 21, co-authored 43 publications receiving 2054 citations. Previous affiliations of Kil Sun Lee include University of São Paulo & National Institutes of Health.
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Journal ArticleDOI
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
Silvio M. Zanata,Marilene H. Lopes,Adriana F. Mercadante,Glaucia N. M. Hajj,Luciana B. Chiarini,Regina Nomizo,Adriana Freitas,A. L. B. Cabral,Kil Sun Lee,Maria A. Juliano,Elizabeth de Oliveira,Saul G. Jachieri,Alma L. Burlingame,Lan Huang,Rafael Linden,Ricardo R. Brentani,Vilma R. Martins +16 more
TL;DR: Cell surface binding and pull‐down experiments showed that recombinant PrPc binds to cellular STI1, and co‐immunoprecipitation assays strongly suggest that both proteins are associated in vivo.
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Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms
Ricardo Cardoso Cassilhas,Kil Sun Lee,Jansen Fernandes,M.G.M. Oliveira,Sergio Tufik,Romain Meeusen,M.T. de Mello +6 more
TL;DR: It is demonstrated that both aerobic and resistance exercise can employ divergent molecular mechanisms but achieve similar results on learning and spatial memory.
Journal ArticleDOI
Uptake and Neuritic Transport of Scrapie Prion Protein Coincident with Infection of Neuronal Cells
Ana Cristina Magalhaes,Gerald S. Baron,Kil Sun Lee,Olivia Steele-Mortimer,David W. Dorward,Marco A. M. Prado,Byron Caughey +6 more
TL;DR: Fluorescent-labeled PrP-res was used to infect a neuronally derived murine cell line and adult hamster cortical neurons and showed that uptake and neuritic transport did not require the presence of endogenous cellular PrP.
Journal ArticleDOI
Endocytic intermediates involved with the intracellular trafficking of a fluorescent cellular prion protein.
Ana C. Magalhães,Juliana de Jesus Aquino Silva,Kil Sun Lee,Kil Sun Lee,Vilma R. Martins,Vania F. Prado,Stephen S. G. Ferguson,Marcus Vinicius Gomez,Ricardo R. Brentani,Marco A. M. Prado +9 more
TL;DR: It is concluded that PrPc internalizes via a dynamin-dependent endocytic pathway and that the protein is targeted to the recycling endosomal compartment via Rab5-positive early endosomes, different from other GPI-anchored proteins.
Journal ArticleDOI
Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells.
Kil Sun Lee,Ana C. Magalhães,Silvio M. Zanata,Silvio M. Zanata,Ricardo R. Brentani,Vilma R. Martins,Marco A. M. Prado +6 more
TL;DR: The data suggest that GFP‐PrPc can be used to follow constitutive and induced PrPc traffic in living cells.