Kim W. Carter

TL;DR: In this article, the Global Lung Function Initiative (GLI) all-age reference values for carbon monoxide were derived for Caucasians aged 5-85 years using the LMS (lambda, mu, sigma) method and the GAMLSS (generalised additive models for location, scale and shape) program.

TL;DR: Increases in ASD was not only limited to advancing paternal or maternal age alone but also to differences parental age including younger or older similarly aged parents as well as disparately aged parents.

TL;DR: The technical implementation of DataSHIELD is described, using a modified R statistical environment linked to an Opal database deployed behind the computer firewall of each DC, which is currently used by the Healthy Obese Project and the Environmental Core Project for the federated analysis of 10 data sets across eight European countries.

TL;DR: The existence of multiple sub isolates, with endogamy maintained to the present day, suggests a general approach to complex disorders in which initial gene mapping could be performed in large families from a single Gypsy group, whereas fine mapping would rely on the informed sampling of the divergent subisolates and searching for the shared genomic region that displays the strongest linkage disequilibrium with the disease.

TL;DR: Using a moderate‐sized cohort selected with extreme BMD, significant association of several members of the Wnt signaling pathway with bone densitometry measures was shown, confirming that extreme truncate selection is a powerful design for quantitative trait association studies of bone phenotypes.