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Knut Johnsen

Researcher at University Hospital of North Norway

Publications -  12
Citations -  542

Knut Johnsen is an academic researcher from University Hospital of North Norway. The author has contributed to research in topics: Population & Ulcerative colitis. The author has an hindex of 7, co-authored 11 publications receiving 470 citations. Previous affiliations of Knut Johnsen include University of Tromsø.

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Journal ArticleDOI

A recent bottleneck of Y chromosome diversity coincides with a global change in culture

Monika Karmin, +124 more
- 01 Apr 2015 - 
TL;DR: A study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples, infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky, and hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
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Interethnic difference in thiopurine methyltransferase activity.

TL;DR: The higher red blood cell thiopurine methyltransferase activity in the Saami population group indicates that these subjects may require higher dosages of thiopirine drugs than Caucasians.
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Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease.

TL;DR: Normalization of mucosal gene expression of cytokines after anti-TNF therapy does not occur in all patients with healed mucosa as judged by endoscopy, but normalization of TNF and/or IL17A expression predicts long-term remission.
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Acetabular dysplasia as an aetiological factor in development of hip osteoarthritis

TL;DR: In this middle-aged Sámi population, there is no evidence for the influence of AD on the development of hip OA and the logistic regression analyses did not show a significant association between AD and OA.
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Normalization of mucosal tumor necrosis factor-α: A new criterion for discontinuing infliximab therapy in ulcerative colitis.

TL;DR: Normalization of mucosal TNF predicts long-term remission after discontinuation of IFX, and mucosal expression levels of IL17A, IL23, IFNG, TGFB, IL6 did not predict long- term remission (>12months).