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Konstantinos Thalassinos
Researcher at University College London
Publications - 87
Citations - 3787
Konstantinos Thalassinos is an academic researcher from University College London. The author has contributed to research in topics: Mass spectrometry & Ion-mobility spectrometry. The author has an hindex of 30, co-authored 79 publications receiving 3237 citations. Previous affiliations of Konstantinos Thalassinos include King's College London & University of Warwick.
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Journal ArticleDOI
An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument
Steven Derek Pringle,Kevin Giles,Jason Lee Wildgoose,Jonathan Williams,Susan E. Slade,Konstantinos Thalassinos,Robert Harold Bateman,Michael T. Bowers,James H. Scrivens +8 more
TL;DR: In this article, the authors presented the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave ion mobility separator/orthogonal acceleration time-of-flight instrument.
Journal ArticleDOI
Recommendations for reporting ion mobility Mass Spectrometry measurements
Valérie Gabelica,Alexandre A. Shvartsburg,Carlos Afonso,Perdita E. Barran,Justin L. P. Benesch,Christian Bleiholder,Michael T. Bowers,Aivett Bilbao,Matthew F. Bush,J. Larry Campbell,Iain D. G. Campuzano,Tim J. Causon,Brian H. Clowers,Colin S. Creaser,Edwin De Pauw,Johann Far,Francisco Fernandez-Lima,John C. Fjeldsted,Kevin Giles,Michael Groessl,Christopher J. Hogan,Stephan Hann,Hugh I. Kim,Ruwan T. Kurulugama,Jody C. May,John A. McLean,Kevin Pagel,Keith Richardson,Mark E. Ridgeway,Frédéric Rosu,Frank Sobott,Konstantinos Thalassinos,Stephen J. Valentine,Thomas Wyttenbach +33 more
TL;DR: A guide to ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements are done, and how to report the results, including the uncertainties of mobility and collision cross section values.
Journal ArticleDOI
A comparison of labeling and label-free mass spectrometry-based proteomics approaches.
Vibhuti J. Patel,Konstantinos Thalassinos,Susan E. Slade,Joanne B. Connolly,Andrew T. Crombie,J. Colin Murrell,James H. Scrivens +6 more
TL;DR: The proteome of the recently discovered bacterium Methylocella silvestris has been characterized using three profiling and comparative proteomics approaches and results obtained have been compared with respect to number of proteins identified, confidence in identification, sequence coverage and agreement of regulated proteins.
Journal ArticleDOI
Characterization of phosphorylated peptides using traveling wave-based and drift cell ion mobility mass spectrometry
Konstantinos Thalassinos,Megan Grabenauer,Susan E. Slade,Gillian R. Hilton,Michael T. Bowers,James H. Scrivens +5 more
TL;DR: A method to calibrate the T-Wave device, to provide estimates of collision cross sections, is presented, and these estimates are in excellent agreement with values obtained on drift cell instrumentation.
Journal ArticleDOI
Travelling wave ion mobility mass spectrometry studies of protein structure: biological significance and comparison with X-ray crystallography and nuclear magnetic resonance spectroscopy measurements
TL;DR: The results illustrate that the TWIMS approach can provide data on three-dimensional protein structures of biological relevance, and the relative stability of gas-phase structures has been investigated, based on their change in cross-section with increase in charge.