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Colin S. Creaser

Researcher at Loughborough University

Publications -  176
Citations -  4775

Colin S. Creaser is an academic researcher from Loughborough University. The author has contributed to research in topics: Mass spectrometry & Ion-mobility spectrometry. The author has an hindex of 34, co-authored 176 publications receiving 4493 citations. Previous affiliations of Colin S. Creaser include University of East Anglia & Leicester Royal Infirmary.

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Recommendations for reporting ion mobility Mass Spectrometry measurements

TL;DR: A guide to ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements are done, and how to report the results, including the uncertainties of mobility and collision cross section values.
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An integrated approach utilizing artificial neural networks and SELDI mass spectrometry for the classification of human tumours and rapid identification of potential biomarkers.

TL;DR: The data from this initial study suggests that application of ANN-based approaches can identify molecular ion patterns which strongly associate with disease grade and that its application to larger cohorts of patient material could potentially facilitate the rapid identification of validated biomarkers having significant clinical (i.e. diagnostic/prognostic) potential for the field of cancer biology.
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Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein

TL;DR: The findings are the first demonstration that CML cells express HLA-associated leukemia-specific immunogenic peptides and provide a sound basis for immunization studies against BCR-ABL.
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Ion mobility spectrometry: a review. Part 1. Structural analysis by mobility measurement

TL;DR: Ion mobility spectrometry (IMS) is an electrophoretic technique that allows ionized analyte molecules to be separated on the basis of their mobilities in the gas phase as mentioned in this paper.
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Direct analysis of pharmaceutical drug formulations using ion mobility spectrometry/quadrupole-time-of-flight mass spectrometry combined with desorption electrospray ionization.

TL;DR: The ability to analyze hard or soft pharmaceutical formulations directly by DESI combined with ion mobility spectrometry/mass spectrometer in approximately 2 min demonstrates the potential applicability of this novel method to pharmaceutical screening of low-molecular-weight drug formulations with high selectivity over the formulation vehicle.