K
Kristina Allers
Researcher at Humboldt University of Berlin
Publications - 2
Citations - 145
Kristina Allers is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Cytotoxic T cell & Innate immune system. The author has an hindex of 1, co-authored 2 publications receiving 3 citations.
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Journal ArticleDOI
Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells
Mario Witkowski,Mario Witkowski,Caroline Tizian,Marta Ferreira-Gomes,Daniela Niemeyer,Daniela Niemeyer,Terry Jones,Terry Jones,Terry Jones,Frederik Heinrich,Stefan Frischbutter,Stefan Angermair,Thordis Hohnstein,Irene Mattiola,Philipp Nawrath,Sophie Mc Ewen,Silvia Zocche,Edoardo Viviano,Gitta Anne Heinz,Marcus Maurer,Uwe Kölsch,Robert Lorenz Chua,Tom Aschman,Christian Meisel,Josefine Radke,Birgit Sawitzki,Jobst Roehmel,Kristina Allers,V. Moos,Thomas Schneider,Leif G. Hanitsch,Marcus A. Mall,Christian Conrad,Helena Radbruch,Claudia U. Duerr,Joseph A. Trapani,Emanuela Marcenaro,Tilmann Kallinich,Victor M. Corman,Victor M. Corman,Florian Kurth,Leif E. Sander,Christian Drosten,Christian Drosten,Sascha Treskatsch,Pawel Durek,Andrey Kruglov,Andrey Kruglov,Andreas Radbruch,Mir-Farzin Mashreghi,Andreas Diefenbach,Andreas Diefenbach +51 more
TL;DR: In this article, the authors show that in severe SARS-CoV-2, natural killer (NK) cells show remarkable defects in virus control, cytokine production and cell-mediated cytotoxicity despite high expression of cytotoxic effector molecules.
Journal ArticleDOI
Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8 + T cells.
Malte Lehmann,Kristina Allers,Claudia Heldt,Jenny Meinhardt,Franziska Schmidt,Yasmina Rodriguez-Sillke,Yasmina Rodriguez-Sillke,Désirée Kunkel,Michael Schumann,Chotima Böttcher,Christiane Stahl-Hennig,Sefer Elezkurtaj,Christian Bojarski,Helena Radbruch,Victor M. Corman,Thomas Schneider,Christoph Loddenkemper,V. Moos,Carl Weidinger,Anja A. Kühl,Britta Siegmund +20 more
TL;DR: In this article, the authors used qRT-PCR and immunohistochemistry to detect SARS-CoV-2 RNA and nucleocapsid protein in duodenal mucosa and identified histomorphological changes of the epithelium, which were characterized by an accumulation of activated intraepithelial CD8+ T cells as well as epithelial apoptosis and subsequent regenerative proliferation.