K
Kunimasa Ohta
Researcher at Kyushu University
Publications - 86
Citations - 2221
Kunimasa Ohta is an academic researcher from Kyushu University. The author has contributed to research in topics: Stem cell & Neural stem cell. The author has an hindex of 25, co-authored 80 publications receiving 2017 citations. Previous affiliations of Kunimasa Ohta include Nagoya University & Kumamoto University.
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Journal ArticleDOI
Shared and distinct functions of RAGS and ELF‐1 in guiding retinal axons
Bruno Monschau,Claus Kremoser,Kunimasa Ohta,Hideaki Tanaka,Tomomi Kaneko,Tomoko Yamada,Claudia Handwerker,Martin Hornberger,Jürgen Löschinger,Elena B. Pasquale,Doyle A. Siever,Michael F. Verderame,Bernhard Müller,Friedrich Bonhoeffer,Uwe Drescher +14 more
TL;DR: Two ligands for Eph‐related receptor tyrosine kinases, RAGS and ELF‐1, have been implicated in the control of development of the retinotectal projection and their biological activities correlate with the strength of interaction with their receptors expressed on RGC axons.
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Draxin, a repulsive guidance protein for spinal cord and forebrain commissures.
Shahidul M. Islam,Yohei Shinmyo,Tatsuya Okafuji,Tatsuya Okafuji,Yuhong Su,Iftekhar Bin Naser,Giasuddin Ahmed,Sanbing Zhang,Sandy Chen,Kunimasa Ohta,Hiroshi Kiyonari,Takaya Abe,Satomi S. Tanaka,Ryuichi Nishinakamura,Toshio Terashima,Toshio Kitamura,Hideaki Tanaka +16 more
TL;DR: Draxin is a previously unknown chemorepulsive axon guidance molecule required for the development of spinal cord and forebrain commissures and is identified as a secreted protein that shares no homology with known guidance cues.
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Plexin: A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions
Kunimasa Ohta,Akihito Mizutani,Atsushi Kawakami,Yasunori Murakami,Yasuyo Kasuya,Shin Takagi,Hideaki Tanaka,Hajime Fujisawa +7 more
TL;DR: Findings indicate that plexin is a novel calcium-dependent cell adhesion molecule and suggest its involvement in specific neuronal cell interaction and/or contact.
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The receptor tyrosine kinase, Cek8, is transiently expressed on subtypes of motoneurons in the spinal cord during development
Kunimasa Ohta,Masaaki Nakamura,Kaoru Hirokawa,Shigeyasu Tanaka,Atsushi Iwama,Toshio Suda,Masayuki Ando,Hideaki Tanaka +7 more
TL;DR: In situ hybridization revealed that Cek8, a member of the eph family, was specifically expressed on motoneurons at the brachial and lumbar segments of the spinal cord which innervate limb muscles, and disappeared after the naturally occurring cell death period.
Journal ArticleDOI
Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin.
Kunimasa Ohta,Kunimasa Ohta,Giuseppe Lupo,Sei Kuriyama,Roger J. Keynes,Christine E. Holt,William A. Harris,Hideaki Tanaka,Shin Ichi Ohnuma +8 more
TL;DR: Biochemical analysis shows that TSK binds directly to both BMP and chordin and forms a ternary complex with them, which indicates that T SK is an essential dorsalizing factor involved in the induction of Hensen's node.