L. Stefan Lohmander

TL;DR: In this paper, the authors monitor levels of synovial fluid and serum pro-inflammatory cytokines and aggrecan ARGS neoepitope, and urine C-terminal type II (CTX-II) and Nterminal Type I (NTX-I) collagen cross-linked telopeptides after acute anterior cruciate ligament (ACL) rupture.

TL;DR: The results do not support a specific level of pain or function that defines an indication for joint replacement, however, a tentative cutpoint for pain and physical function levels is proposed for further evaluation.

TL;DR: Proteoglycan synthesis can be described as occurring in two stages, translation and N‐glycosylation of a coreprotein precursor which has a long half‐life in the rough endoplasmic reticulum, followed by extensive rapid modification in the Golgi complex in which the majority of glycosaminoglycan and oligosaccharide chains are added to the core protein precursor with subsequent rapid secretion into the extracellular matrix.

TL;DR: Evidence for linkage in this family suggests that a gene for susceptibility to Hip OA exists on chromosome 16p, an independent identification of a susceptibility locus previously reported for hip OA in this geographic region.

TL;DR: If being without an artificial joint implant is considered to be beneficial, then HTO is an excellent alternative to knee arthroplasty in younger and/or physically active patients suffering from knee osteoarthritis.