L
Lasha Gogokhia
Researcher at Cornell University
Publications - 17
Citations - 1538
Lasha Gogokhia is an academic researcher from Cornell University. The author has contributed to research in topics: Inflammatory bowel disease & Internal medicine. The author has an hindex of 8, co-authored 13 publications receiving 1172 citations. Previous affiliations of Lasha Gogokhia include St Mary's Hospital & NewYork–Presbyterian Hospital.
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Journal ArticleDOI
Phage Therapy in Clinical Practice: Treatment of Human Infections
Elizabeth Kutter,Daniel De Vos,Guram Gvasalia,Zemphira Alavidze,Lasha Gogokhia,Sarah J. Kuhl,Stephen T. Abedon +6 more
TL;DR: This review aims to provide an overview of the potential of phage therapy as a means of treating or preventing human diseases and to explore the phage Therapy state of the art as currently practiced by physicians in various pockets ofphage therapy activity around the world.
Journal ArticleDOI
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Lasha Gogokhia,Lasha Gogokhia,Kate Buhrke,Rickesha Bell,Brenden Hoffman,D. Garrett Brown,Christin Hanke-Gogokhia,Nadim J. Ajami,Matthew C. Wong,Arevik Ghazaryan,John F. Valentine,Nathan T. Porter,Eric C. Martens,Ryan M. O'Connell,Vinita Jacob,Ellen Scherl,Carl V. Crawford,W. Zac Stephens,Sherwood R. Casjens,Randy S. Longman,June L. Round +20 more
TL;DR: Results indicate that bacteriophages can alter mucosal immunity to impact mammalian health and reduce phages compared to non-responders.
Journal ArticleDOI
Chronic wounds and the medical biofilm paradigm.
R.D. Wolcott,Daniel D. Rhoads,M E Bennett,B M Wolcott,Lasha Gogokhia,J W Costerton,Scot E. Dowd +6 more
TL;DR: The development of treatments for wound biofilms raises the prospect that chronic wounds can be treated, potentially saving many patients' lives, and this work contributes towards that goal.
Journal ArticleDOI
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice
Tyson R. Chiaro,Ray Soto,W. Zac Stephens,Jason L. Kubinak,Charisse Petersen,Lasha Gogokhia,Rickesha Bell,Julio C. Delgado,Julio C. Delgado,James E. Cox,Warren P. Voth,Jessica C.S. Brown,David J. Stillman,Ryan M. O'Connell,Anne E. Tebo,Anne E. Tebo,June L. Round +16 more
TL;DR: It is demonstrated that increased colonization of the mouse gut with S. cerevisiae aggravated colitis by increasing purine metabolism, leading to greater damage of the gut epithelia, and a positive correlation between elevated uric acid and anti-yeast antibodies in human sera is found.
Journal ArticleDOI
MHC Variation Sculpts Individualized Microbial Communities That Control Susceptibility to Enteric Infection
Jason L. Kubinak,W. Zac Stephens,Ray Soto,Charisse Petersen,Tyson R. Chiaro,Lasha Gogokhia,Rickesha Bell,Nadim J. Ajami,Joseph F. Petrosino,Linda C. Morrison,Wayne K. Potts,Peter E. Jensen,Ryan M. O'Connell,June L. Round +13 more
TL;DR: It is found that MHC genotype significantly influences antibody responses against commensals in the gut, and that these responses are correlated with the establishment of unique microbial communities.