J
John F. Valentine
Researcher at University of Utah
Publications - 154
Citations - 7557
John F. Valentine is an academic researcher from University of Utah. The author has contributed to research in topics: Seagrass & Inflammatory bowel disease. The author has an hindex of 43, co-authored 140 publications receiving 6754 citations. Previous affiliations of John F. Valentine include University of South Alabama & Veterans Health Administration.
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Journal ArticleDOI
Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease
TL;DR: Evidence that Mycobacterium avium subspecies paratuberculosis (MAP) might be a cause of Crohn's disease is added to by detecting viable MAP in peripheral blood in a higher proportion of individuals with Crohn't disease than in controls.
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Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.
Uma Mahadevan,Douglas C. Wolf,Marla Dubinsky,Antoine Cortot,Scott D. Lee,Corey A. Siegel,Thomas A. Ullman,Sarah C. Glover,Sarah C. Glover,John F. Valentine,David T. Rubin,Jocelyn Miller,Maria T. Abreu +12 more
TL;DR: CZP has the lowest level of placental transfer, based on levels measured in cords and infants at birth, of the drugs tested; the TNF antagonists IFX and ADA are transferred across the placenta and can be detected in babies at birth.
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Plant-herbivore interactions in seagrass meadows
TL;DR: The major conclusion is that, in contrast to what has been reported in much of the literature on food webs in seagrass meadows, a diverse grazing pathway continues to represent an important conduit for the transfer of energy from the primary producers to higher order consumers.
Journal ArticleDOI
Sargramostim for Active Crohn's Disease
Joshua R. Korzenik,Brian K. Dieckgraefe,John F. Valentine,John F. Valentine,Diana F. Hausman,Mark J. Gilbert +5 more
TL;DR: This study was negative for the primary end point, but findings for the secondary end points suggest that sargramostim therapy decreased disease severity and improved the quality of life in patients with active Crohn's disease.
Journal ArticleDOI
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Lasha Gogokhia,Lasha Gogokhia,Kate Buhrke,Rickesha Bell,Brenden Hoffman,D. Garrett Brown,Christin Hanke-Gogokhia,Nadim J. Ajami,Matthew C. Wong,Arevik Ghazaryan,John F. Valentine,Nathan T. Porter,Eric C. Martens,Ryan M. O'Connell,Vinita Jacob,Ellen Scherl,Carl V. Crawford,W. Zac Stephens,Sherwood R. Casjens,Randy S. Longman,June L. Round +20 more
TL;DR: Results indicate that bacteriophages can alter mucosal immunity to impact mammalian health and reduce phages compared to non-responders.