L
Laura Chiossone
Researcher at Aix-Marseille University
Publications - 29
Citations - 3035
Laura Chiossone is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Interleukin 21 & Lymphokine-activated killer cell. The author has an hindex of 19, co-authored 28 publications receiving 2335 citations. Previous affiliations of Laura Chiossone include French Institute of Health and Medical Research & Istituto Giannina Gaslini.
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Journal ArticleDOI
Maturation of mouse NK cells is a 4-stage developmental program.
Laura Chiossone,Julie Chaix,Julie Chaix,Nicolas Fuseri,Claude Roth,Eric Vivier,Thierry Walzer,Thierry Walzer +7 more
TL;DR: A 4-stage model ofNK-cell maturation appears to be associated with a progressive acquisition of NK-cell effector functions.
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Natural killer cells and other innate lymphoid cells in cancer.
TL;DR: An overview of the field is provided and current immunotherapeutic approaches for solid tumours and haematological malignancies are summarized and the authors highlight the current immunotherapy trials that are targeting NK cells to treat patients with cancer.
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Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
Thierry Walzer,Laura Chiossone,Julie Chaix,Andrew R. Calver,Claude Carozzo,Claude Carozzo,Laure Garrigue-Antar,Laure Garrigue-Antar,Yannick Jacques,Yannick Jacques,Myriam Baratin,Elena Tomasello,Eric Vivier +12 more
TL;DR: It is found that S1P5 was required for the mobilization of NK cells to inflamed organs and the possibility that NK cell trafficking may be manipulated by therapies specifically targeting S1p5 is raised.
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Tumor-Infiltrating Natural Killer Cells
Beatriz Cózar,Marco Greppi,Sabrina Carpentier,Emilie Narni-Mancinelli,Laura Chiossone,Eric Vivier +5 more
TL;DR: An overview of what is known about NK tumor infiltration and surveillance and about the mechanisms by which NK cells become dysfunctional is provided and the functions of tumor-infiltrating NK cells may be impaired.
Journal ArticleDOI
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses.
Laura Chiossone,Romana Conte,Grazia Maria Spaggiari,Martina Serra,Cristina Romei,Francesca Bellora,Flavio Becchetti,Antonio Andaloro,Lorenzo Moretta,Cristina Bottino +9 more
TL;DR: The data show that MMSC induce the generation of a novel type of alternatively activated macrophages capable of suppressing both innate and adaptive immune responses, which may help to better understand the role of MSCs in healthy tissues and inflammatory diseases including cancer.