Lee Rowen

TL;DR: It is demonstrated that interspecific sequence conservation can provide a systematic guide to the identification of functional cis-regulatory elements within a large expanse of genomic DNA.

TL;DR: Comparison of human and mouse genomic sequence at the border of the major histocompatibility complex (MHC) class’II and class III regions revealed a locus encoding six exons with homology to the butyrophilin gene family and the location of a previously decribed gene, testis-specific basic protein (TSBP).

TL;DR: It is suggested that the expression of a large Dscam repertoire is more important for the development and function of the insect nervous system than the actual sequence of each isoform.

TL;DR: The 29-residue ribonucleotide primer formed by primase at the origin of phage G4 DNA replication was shorter in the presence of deoxynucleoside triphosphates (dNTPs), indicating that primase is able to add either a ribon nucleotide or deoxyribon DNA transcript to the 3'-OH of either of ribo residue or a deoxy residue of the primer terminus.

TL;DR: A comparative genomics approach is taken to identify features that may be involved in the dynamic evolution of this gene family and in the transcriptional control that results in a single OR gene expressed per olfactory neuron.