Leila R. Zelnick

TL;DR: Among US adults with diabetes from 1988 to 2014, the overall prevalence of diabetic kidney disease did not change significantly, whereas the prevalence of albuminuria declined and thePrevalence of reduced eGFR increased.

TL;DR: Clonal mosaicism for large chromosomal anomalies (duplications, deletions and uniparental disomy) is detected using SNP microarray data from over 50,000 subjects recruited for genome-wide association studies to identify common deleted regions with genes previously associated with hematological cancers.

TL;DR: CKD was associated with an increased risk of HF that was similar in magnitude to CHD and greater than stroke and Efforts to improve health outcomes for patients with CKD should prioritize HF in addition toCHD prevention.

TL;DR: Diabetes is strongly associated with both albuminuria and reduced GFR independent of demographics and hypertension, contributing substantially to the burden of CKD in the United States.

TL;DR: Identifying two molecularly distinct AKI subphenotypes with different clinical outcomes and responses to vasopressin therapy are identified and may be useful for predictive enrichment in clinical trials.