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M. Geoffrey Hayes

Researcher at Northwestern University

Publications -  122
Citations -  10393

M. Geoffrey Hayes is an academic researcher from Northwestern University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 44, co-authored 113 publications receiving 8885 citations. Previous affiliations of M. Geoffrey Hayes include University of Chicago & Greifswald University Hospital.

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Defining the role of common variation in the genomic and biological architecture of adult human height

Andrew R. Wood, +444 more
- 01 Nov 2014 - 
TL;DR: This article identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height, and all common variants together captured 60% of heritability.
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Genome-partitioning of genetic variation for complex traits using common SNPs

Jian Yang, +24 more
- 01 Jun 2011 - 
TL;DR: The results provide further evidence that a substantial proportion of heritability is captured by common SNPs, that height, BMI and QTi are highly polygenic traits, and that the additive variation explained by a part of the genome is approximately proportional to the total length of DNA contained within genes therein.
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Insulin gene mutations as a cause of permanent neonatal diabetes

Julie Støy, +17 more
- 18 Sep 2007 - 
TL;DR: Ten heterozygous mutations in the human insulin gene are reported in 16 probands with neonatal diabetes, and it is predicted that they prevent normal folding and progression of proinsulin in the insulin secretory pathway.
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Detectable clonal mosaicism from birth to old age and its relationship to cancer.

Cathy C. Laurie, +72 more
- 01 Jun 2012 - 
TL;DR: Clonal mosaicism for large chromosomal anomalies (duplications, deletions and uniparental disomy) is detected using SNP microarray data from over 50,000 subjects recruited for genome-wide association studies to identify common deleted regions with genes previously associated with hematological cancers.
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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Nicole M. Warrington, +245 more
- 01 May 2019 - 
TL;DR: An expanded GWAS of birth weight and subsequent analysis using structural equation modeling and Mendelian randomization decomposes maternal and fetal genetic contributions and causal links between birth weight, blood pressure and glycemic traits.