Lesley F Drynan

TL;DR: It is found that nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, which indicates they are distinct, previously unknown members of the lymphoid lineage.

TL;DR: These findings identify nuocytes as a novel cell type in allergic lung inflammation and an innate source of IL-13 that can directly induce AHR in the absence ofIL-13-producing CD4(+) T cells.

TL;DR: This mouse model suggests that a p53-dependent mechanism underlies the pathophysiology of the 5q– syndrome, and rescues the progenitor cell defect, restoring common myeloid progensitor and megakaryocytic-erythroid progenitors and hematopoietic stem cell bone marrow populations.

TL;DR: These findings establish a direct role for SBDS and EFL1 in catalyzing the translational activation of ribosomes in all eukaryotes, and define SDS as a ribosomopathy caused by uncoupling GTP hydrolysis from eIF6 release.

TL;DR: It is concluded that there is no mandatory role for LMO2 in lymphoid development, implying that its specific role in T-cell tumorigenesis results from a reprogramming of gene expression after enforced expression inT-cell precursors.