Veera Panova

TL;DR: It is found that nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, which indicates they are distinct, previously unknown members of the lymphoid lineage.

TL;DR: This paper showed that IL-33 plays a critical role in the rapid induction of airway contraction by stimulating the prompt expansion of IL-13-producing type 2 innate lymphoid cells, whereas IL-25 induced responses are slower and less potent.

TL;DR: It is found that type‐2 pneumocytes constitute the major source of IL‐33 upon allergic lung inflammation following exposure to OVA, fungal extract or ragweed pollen and a potential mechanism of action by which IL‐ 33 rapidly initiates type-2 immune responses is demonstrated.

TL;DR: It is demonstrated that type-2 immune-associated neutrophil infiltration is regulated by the mouse RNase A homologue, eosinophil-associated ribonuclease 11 (Ear11), which is secreted by AAM downstream of IL-25-stimulated ILC2, which helps maintain tissue neutrophils at homoeostasis and during type-1 reactions when chemokine-producing classically activated macrophages are infrequently elicited.

TL;DR: In this paper , a lymph node resident, CD169-lineage, CSF1R-blockade-resistant precursor is prepositioned in the follicle to prevent secondary necrosis and autoimmune activation by intracellular self antigens.