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Leyla R. Davis
Researcher at University of Texas Health Science Center at San Antonio
Publications - 13
Citations - 707
Leyla R. Davis is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Population & Microbiome. The author has an hindex of 7, co-authored 11 publications receiving 560 citations. Previous affiliations of Leyla R. Davis include Max Planck Society & Imperial College London.
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Journal ArticleDOI
Mitigating amphibian disease: strategies to maintain wild populations and control chytridiomycosis
Douglas C. Woodhams,Douglas C. Woodhams,Jaime Bosch,Cheryl J. Briggs,Scott D. Cashins,Leyla R. Davis,Antje Lauer,Erin Muths,Robert Puschendorf,Benedikt R. Schmidt,Brandon Sheafor,Jamie Voyles +11 more
TL;DR: It is suggested that disease mitigation not focus exclusively on the elimination or containment of the pathogen, or on the captive breeding of amphibian hosts, rather, successful disease mitigation must be context specific with epidemiologically informed strategies to manage already infected populations by decreasing pathogenicity and host susceptibility.
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Antifungal isolates database of amphibian skin-associated bacteria and function against emerging fungal pathogens
Douglas C. Woodhams,Ross A. Alford,Rachael E. Antwis,Holly M. Archer,Matthew H. Becker,Lisa K. Belden,Sara C. Bell,Molly C. Bletz,Joshua H. Daskin,Leyla R. Davis,Sandra V. Flechas,Antje Lauer,Antonio Gonzalez,Reid N. Harris,Whitney M. Holden,Myra C. Hughey,Roberto Ibáñez,Rob Knight,Jordan G. Kueneman,Falitiana C. E. Rabemananjara,Laura K. Reinert,Louise A. Rollins-Smith,Franklin Roman-Rodriguez,Stephanie D. Shaw,Jenifer B. Walke,Valerie J. McKenzie +25 more
TL;DR: This work presents a comprehensive Antifungal Isolates Database of amphibian skin-associated bacteria that have been cultured, isolated, and tested for antif fungus properties, and provides empirical data for comparative and bioinformatic studies.
Journal ArticleDOI
Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster
Natasha Arora,Verena J. Schuenemann,Günter Jäger,Alexander Peltzer,Alexander Seitz,Alexander Herbig,Michal Strouhal,Linda Grillová,Leonor Sánchez-Busó,Leonor Sánchez-Busó,Denise Kühnert,Kirsten I. Bos,Leyla R. Davis,Lenka Mikalová,Sylvia M. Bruisten,Peter Komericki,Patrick French,Paul R. Grant,María A. Pando,Lucía Gallo Vaulet,Marcelo Rodríguez Fermepin,Antonio Luis López Martínez,Arturo Centurion-Lara,Lorenzo Giacani,Steven J. Norris,David Šmajs,Philipp P. Bosshard,Fernando González-Candelas,Kay Nieselt,Johannes Krause,Homayoun C. Bagheri +30 more
TL;DR: DNA capture and whole-genome sequencing are used to successfully interrogate genome-wide variation from syphilis patient specimens, combined with laboratory samples of TPA and two other subspecies, indicating that the TPA strains examined share a common ancestor after the fifteenth century, within the early modern era.
Journal ArticleDOI
Stability of microbiota facilitated by host immune regulation: informing probiotic strategies to manage amphibian disease.
Denise Küng,Laurent Bigler,Leyla R. Davis,Brian Gratwicke,Edgardo Griffith,Douglas C. Woodhams,Douglas C. Woodhams +6 more
TL;DR: The discovery of strong colonization resistance of skin microbiota suggests a well-regulated, rather than dynamic, host-symbiont relationship, and suggests that probiotic therapies aiming to enhance host immunity may require an approach that circumvents host mechanisms maintaining equilibrium in microbial communities.
Journal ArticleDOI
IL‐1 receptor antagonist, anakinra, prevents myocardial dysfunction in a mouse model of Kawasaki disease vasculitis and myocarditis
M Gorelik,M Gorelik,Youngho Lee,Masanori Abe,Thomas Andrews,Leyla R. Davis,Jean L. Patterson,Shuang Chen,Shuang Chen,Timothy R. Crother,Timothy R. Crother,Gregory J. Aune,M. Noval Rivas,M. Noval Rivas,Moshe Arditi,Moshe Arditi +15 more
TL;DR: Findings further support the potential beneficial effects of IL‐1Ra therapy in preventing the cardiovascular complications in acute KD patients, including the myocarditis and myocardial dysfunction associated with acute KD.