L
Li Rong Yu
Researcher at Science Applications International Corporation
Publications - 14
Citations - 1084
Li Rong Yu is an academic researcher from Science Applications International Corporation. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 11, co-authored 14 publications receiving 1022 citations. Previous affiliations of Li Rong Yu include Pacific Northwest National Laboratory & National Institutes of Health.
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Journal ArticleDOI
Regulation of androgen receptor activity by tyrosine phosphorylation
Zhiyong Guo,Bojie Dai,Tianyun Jiang,Kexin Xu,Yingqiu Xie,Oekyung Kim,Issa Nesheiwat,Xiangtian Kong,Jonathan Melamed,Venkatesh D. Handratta,Vincent C. O. Njar,Angela Brodie,Li Rong Yu,Timothy D. Veenstra,Hegang Chen,Yun Qiu +15 more
TL;DR: It is reported that tyrosine phosphorylation of AR is induced by growth factors and elevated in hormone-refractory prostate tumors and such modification may be important for prostate tumor growth under androgen-depleted conditions.
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Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation.
Young H. Kang,Jung-Eun Park,Li Rong Yu,Nak Kyun Soung,Sang Moon Yun,Jeong K. Bang,Yeon Sun Seong,Hongtao Yu,Susan H. Garfield,Timothy D. Veenstra,Kyung S. Lee +10 more
TL;DR: Plk1 self-regulates the Plk1-PBIP1 interaction to timely localize to the kinetochores and promote proper chromosome segregation.
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Coupling morphogenesis to mitotic entry
Krisada Sakchaisri,Satoshi Asano,Li Rong Yu,Mark J. Shulewitz,Chong J. Park,Jung-Eun Park,Young Wook Cho,Timothy D. Veenstra,Jeremy Thorner,Kyung S. Lee +9 more
TL;DR: It is shown that two other kinases targeted sequentially to the neck, Cla4/PAK and Cdc5/Polo, are responsible for stepwise phosphorylation and down-regulation of Swe1, which links assembly of a cellular structure to passage into mitosis.
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RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity.
Sook Lee,Jon D. Shuman,Jon D. Shuman,Tad Guszczynski,Krisada Sakchaisri,Thomas Sebastian,Terry D. Copeland,Maria Miller,Michael S. Cohen,Jack Taunton,Robert C. Smart,Zhen Xiao,Li Rong Yu,Timothy D. Veenstra,Peter F. Johnson +14 more
TL;DR: It is shown that C/EBPβ DNA binding is autorepressed and becomes activated by the Ras-Raf-MEK-ERK-p90RSK cascade and RSK-mediated phosphorylation of a bifunctional residue in the leucine zipper that regulates DNA binding and homodimerization and thereby promotes cell cycle arrest.
Journal ArticleDOI
Global Analysis of the Cortical Neuron Proteome
Li Rong Yu,Thomas P. Conrads,Takuma Uo,Yoshito Kinoshita,Richard S. Morrison,David A. Lucas,King C. Chan,Josip Blonder,Haleem J. Issaq,Timothy D. Veenstra +9 more
TL;DR: The results presented here provide the broadest proteome coverage for a mammalian cell to date and show that MS-based proteomics has the potential to provide high coverage of the proteins expressed within a cell.