Linda K. Johnson

TL;DR: Functional evidence is provided supporting a causative role of maternal obesity-associated infant dysbiosis in childhood obesity and NAFLD by showing that maternal Obesity-shaped infant gut microbiome induces macrophage dysfunction, inflammation, and diet-induced metabolic disease in germ-free mice.

TL;DR: This work shows that DDR2 depletion increases sensitivity to anti–PD-1 treatment compared to monotherapy, and provides strong scientific rationale for targeting DDR2 in combination with PD-1 inhibitors.

TL;DR: A viewpoint from the National Institutes of Health on measures needed to enhance rigor and reproducibility is given, as well as an overview of the role of the Institutional Animal Care and Use Committee in this regard.

TL;DR: The potential for the spread of infection, zoonosis, and adverse effects on research demonstrate that surveillance for S. zooepidemicus should be considered in a biomedical research environment.

TL;DR: RNA-seq analysis suggested that expression of coagulation factor XI (FXI) is downregulated in livers of I278T mice, and downregulation of FXI may contribute to the lack of prothrombotic tendency in I 278T mice.