L
Lorenz Trümper
Researcher at University of Göttingen
Publications - 276
Citations - 22696
Lorenz Trümper is an academic researcher from University of Göttingen. The author has contributed to research in topics: Lymphoma & Diffuse large B-cell lymphoma. The author has an hindex of 53, co-authored 260 publications receiving 19534 citations. Previous affiliations of Lorenz Trümper include Deutsche Forschungsgemeinschaft & University of Cologne.
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Journal ArticleDOI
Treatment response to idelalisib in a patient with immunodeficiency-associated Burkitt lymphoma harboring a PIK3CA H1047R mutation.
Annalen Bleckmann,Sascha Dierks,Hans-Ulrich Schildhaus,Niels Hellige,Ulrike Bacher,Lorenz Trümper,Gerald Wulf +6 more
TL;DR: The successful salvage therapy with idelalisib is reported in a patient with relapsed immunodeficiency-associated BL exhibiting a TP53 mutation and a H1047R mutation in the PIK3CA gene, which is a highly selective inhibitor of the PI3K delta isoform.
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Characterization of HLA-DR-restricted T-cell epitopes derived from human proteinase 3.
TL;DR: T-cell responses against proteinase 3 are analyzed using synthetic peptides predicted to serve as HLA-DR-restricted epitopes to study the role of CD4+ TH- and Treg-cells in immune responses against PRTN3 in leukemia patients and patients with Wegener's disease.
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Extramedullary hematopoiesis in the paravertebral space
Björn-W. Raab,Henry Simon,Heinz Schmidtberger,Uwe Fischer,Rolf Vosshenrich,Lorenz Trümper,Eckhardt Grabbe +6 more
TL;DR: Clinical presentation, knowledge of the underlying disease and of imaging findings are essential in the diagnosis of extramedullary hematopoiesis, and MRI is the imaging modality of choice in the primary diagnosis.
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Abundant expression of spliced HDM2 in Hodgkin lymphoma cells does not interfere with p14(ARF) and p53 binding.
Benjamin Stürzenhofecker,Thilo Schlott,Thomas Quentin,Dieter Kube,Wolfram Jung,Lorenz Trümper +5 more
TL;DR: It is suggested that HDM2-sv have no significant disturbing influence on the interaction of these proteins, and co-localization of the potential binding partners HDM 2/p14ARF and HDM/p53 was found in HL cell lines.
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Whole-body Vibration Training as a Supportive Therapy During Allogeneic Haematopoietic Stem Cell Transplantation – A Randomised Controlled Trial
Tobias S Kaeding,Tobias S Kaeding,Marcel Frimmel,Florian Treondlin,Klaus Jung,Wolfram Jung,Gerald Wulf,Lorenz Trümper,Justin Hasenkamp +8 more
TL;DR: This research presents a novel and scalable approach called “Smart Bioinformatics” that automates the very labor-intensive and therefore time-heavy and expensive and therefore expensive and expensive process of stem cell transplantation.