L
Lorenz Trümper
Researcher at University of Göttingen
Publications - 276
Citations - 22696
Lorenz Trümper is an academic researcher from University of Göttingen. The author has contributed to research in topics: Lymphoma & Diffuse large B-cell lymphoma. The author has an hindex of 53, co-authored 260 publications receiving 19534 citations. Previous affiliations of Lorenz Trümper include Deutsche Forschungsgemeinschaft & University of Cologne.
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Journal ArticleDOI
Peripheral T-cell lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Francesco d'Amore,Philippe Gaulard,Lorenz Trümper,Paolo Corradini,Won Seog Kim,Lena Specht,M. Bjerregaard Pedersen,Marco Ladetto +7 more
TL;DR: The aim of this work is to provide a systematic review and meta-analysis of the literature on canine coronavirus infection and its role in mortality and morbidity and to establish a smoking cessation strategy for this disease.
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A Comprehensive Microarray-Based DNA Methylation Study of 367 Hematological Neoplasms
José I. Martín-Subero,Ole Ammerpohl,Marina Bibikova,Eliza Wickham-Garcia,Xabier Agirre,Sara Alvarez,Monika Brüggemann,Stefanie Bug,María José Calasanz,Martina Deckert,Martin Dreyling,Ming Q. Du,Jan Dürig,Martin J. S. Dyer,Jian-Bing Fan,Stefan Gesk,Martin-Leo Hansmann,Lana Harder,Sylvia Hartmann,Wolfram Klapper,Ralf Küppers,Manuel Montesinos-Rongen,Inga Nagel,Christiane Pott,Julia Richter,Jose Roman-Gomez,Marc Seifert,Harald Stein,Javier Suela,Lorenz Trümper,Inga Vater,Felipe Prosper,Claudia Haferlach,Juan C. Cigudosa,Reiner Siebert +34 more
TL;DR: The DNA methylation profile of a wide range of different HNs entities was characterized, with a significant correlation between the number of hypermethylated and hypomethylated genes in several mature B-cell neoplasias, but not in precursor B- and T-cell leukemias.
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β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
Florian Klemm,Annalen Bleckmann,Laila Siam,H.N. Chuang,Eva Rietkötter,Daniel Behme,Matthias Schulz,M. Schaffrinski,S. Schindler,Lorenz Trümper,Frank Kramer,Tim Beissbarth,Christine Stadelmann,Claudia Binder,Tobias Pukrop +14 more
TL;DR: In this paper, the role of WNT signaling for primary breast cancers of the basal-like subtype and as a predictor of brain metastasis has been described, but a responsible WNT ligand has not been identified.
Journal ArticleDOI
A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia
Ulrich Steidl,Christian Steidl,Christian Steidl,Alexander K. Ebralidze,Björn Chapuy,Hye-Jung Han,Britta Will,Britta Will,Frank Rosenbauer,Frank Rosenbauer,Annegret Becker,Katharina Wagner,Katharina Wagner,Steffen Koschmieder,Steffen Koschmieder,Susumu Kobayashi,Daniel B. Costa,Thomas Schulz,Karen B. O'Brien,Roel G.W. Verhaak,Ruud Delwel,Detlef Haase,Lorenz Trümper,Jürgen Krauter,Terumi Kohwi-Shigematsu,Frank Griesinger,Daniel G. Tenen +26 more
TL;DR: A SNP within a distal enhancer that is associated with a subtype of leukemia and exerts a deleterious effect through remote transcriptional dysregulation in specific progenitor subtypes is identified.
Journal ArticleDOI
Mantle-cell lymphomas have more widespread disease and a slower response to chemotherapy compared with follicle-center lymphomas: results of a prospective comparative analysis of the German Low-Grade Lymphoma Study Group.
Wolfgang Hiddemann,Michael Unterhalt,Richard Herrmann,H H Wöltjen,E.-D. Kreuser,Lorenz Trümper,M. Reuss-Borst,E Terhardt-Kasten,M Busch,Andreas Neubauer,Ursula B. Kaiser,R D Hanrath,H Middeke,G Helm,Mathias Freund,Harald Stein,M. Tiemann,Reza Parwaresch +17 more
TL;DR: In both subtypes, patients with less than two residual lymphoma manifestations in remission experienced a relatively good prognosis with an estimated 5-year survival of greater than 60% for MCL and greater than 75% for FCL.