L
Louis Guzzi
Researcher at Florida Hospital Orlando
Publications - 9
Citations - 614
Louis Guzzi is an academic researcher from Florida Hospital Orlando. The author has contributed to research in topics: Internal medicine & Heparin-induced thrombocytopenia. The author has an hindex of 4, co-authored 7 publications receiving 356 citations.
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Journal ArticleDOI
Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference: A Consensus Statement.
Marlies Ostermann,Alexander Zarbock,Stuart L. Goldstein,Kianoush Kashani,Etienne Macedo,Raghavan Murugan,Max Bell,Lui G. Forni,Louis Guzzi,Michael Joannidis,Sandra L. Kane-Gill,Matthieu Legrand,Ravindra L. Mehta,Patrick T. Murray,Peter Pickkers,Mario Plebani,John R. Prowle,Zaccaria Ricci,Thomas Rimmelé,Mitchell H. Rosner,Andrew D. Shaw,John A. Kellum,Claudio Ronco +22 more
TL;DR: Recommendations were that a combination of damage and functional biomarkers, along with clinical information, be used to identify high-risk patient groups, improve the diagnostic accuracy of AKI, improve processes of care, and assist the management ofAKI.
Journal ArticleDOI
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation
Jean Louis Vincent,Mayakonda K. Ramesh,David Ernest,Steven P. LaRosa,Jan Pachl,Naoki Aikawa,Eric Hoste,Howard Levy,Joe Hirman,Marcel Levi,Mradul Kumar Daga,Demetrios J. Kutsogiannis,Mark Crowther,Gordon R. Bernard,Jacques Devriendt,Joan Vidal Puigserver,Daniel U. Blanzaco,Charles T. Esmon,Joseph E. Parrillo,Louis Guzzi,Seton J. Henderson,Chaicharn Pothirat,Parthiv Mehta,Jawed Fareed,Deepak Talwar,Kazuhisa Tsuruta,Kenneth J. Gorelick,Yutaka Osawa,Inder Kaul +28 more
TL;DR: ART-123 is a safe intervention in critically ill patients with sepsis and suspected disseminated intravascular coagulation and evidence suggestive of efficacy supporting further development of this drug in sepsi-associated coagulopathy is provided.
Journal ArticleDOI
Effect of renal function on argatroban therapy in heparin-induced thrombocytopenia
TL;DR: In this large cohort of HIT patients with normal hepatic function and varying levels of renal function, argatroban administered in accordance with current recommendations provided adequate levels of anticoagulation and was well tolerated.
Journal ArticleDOI
Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel
Louis Guzzi,Tobias Bergler,Brian Binnall,Daniel T. Engelman,Lui G. Forni,Lui G. Forni,Michael J. Germain,Eric Gluck,Ivan Göcze,Michael Joannidis,Jay L. Koyner,V. Seenu Reddy,Thomas Rimmelé,Claudio Ronco,Julien Textoris,Alexander Zarbock,John A. Kellum +16 more
TL;DR: Patients undergoing major surgery, those who were hemodynamically unstable, or those with sepsis appear to be priority patient populations for testing kidney stress using the first FDA-approved test to assess risk for acute kidney injury, [TIMP-2].
Journal ArticleDOI
Limiting Acute Kidney Injury Progression In Sepsis: Study Protocol and Trial Simulation.
Luca Molinari,Fabienne Heskia,Sadudee Peerapornratana,Claudio Ronco,Louis Guzzi,Seth Toback,Robert Birch,Hadi Beyhaghi,Thomas Kwan,J. Patrick Kampf,Donald M. Yealy,John A. Kellum +11 more
TL;DR: The Limiting acute kidney injury progression in sepsis protocol algorithm is therefore feasible in terms of identifying suitably high-risk individuals for kidney-sparing septis bundle as mentioned in this paper.