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Lucas Q. Ton
Researcher at University of Notre Dame
Publications - 4
Citations - 2098
Lucas Q. Ton is an academic researcher from University of Notre Dame. The author has contributed to research in topics: Gene & Anopheles gambiae. The author has an hindex of 4, co-authored 4 publications receiving 2034 citations.
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Journal ArticleDOI
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
Robert A. Holt,G. Mani Subramanian,Aaron L. Halpern,Granger G. Sutton,Rosane Charlab,Deborah R. Nusskern,Patrick Wincker,Andrew G. Clark,José M. C. Ribeiro,Ron Wides,Steven L. Salzberg,Brendan J. Loftus,Mark Yandell,William H. Majoros,William H. Majoros,Douglas B. Rusch,Zhongwu Lai,Cheryl L. Kraft,Josep F. Abril,Véronique Anthouard,Peter Arensburger,Peter W. Atkinson,Holly Baden,Véronique de Berardinis,Danita Baldwin,Vladimir Benes,Jim Biedler,Claudia Blass,Randall Bolanos,Didier Boscus,Mary Barnstead,Shuang Cai,Kabir Chatuverdi,George K. Christophides,Mathew A. Chrystal,Michele Clamp,Anibal Cravchik,Val Curwen,Ali N Dana,Arthur L. Delcher,Ian M. Dew,Cheryl A. Evans,Michael Flanigan,Anne Grundschober-Freimoser,Lisa Friedli,Zhiping Gu,Ping Guan,Roderic Guigó,Maureen E. Hillenmeyer,Susanne L. Hladun,James R. Hogan,Young S. Hong,Jeffrey Hoover,Olivier Jaillon,Zhaoxi Ke,Zhaoxi Ke,Chinnappa D. Kodira,Kokoza Eb,Anastasios C. Koutsos,Ivica Letunic,Alex Levitsky,Yong Liang,Jhy-Jhu Lin,Jhy-Jhu Lin,Neil F. Lobo,John Lopez,Joel A. Malek,Tina C. McIntosh,Stephan Meister,Jason R. Miller,Clark M. Mobarry,Emmanuel Mongin,Sean D. Murphy,David A. O'Brochta,Cynthia Pfannkoch,Rong Qi,Megan A. Regier,Karin A. Remington,Hongguang Shao,Maria V. Sharakhova,Cynthia Sitter,Jyoti Shetty,Thomas J. Smith,Renee Strong,Jingtao Sun,Dana Thomasova,Lucas Q. Ton,Pantelis Topalis,Zhijian Tu,Maria F. Unger,Brian P. Walenz,Aihui Wang,Jian Wang,Mei Wang,X. Wang,Kerry J. Woodford,Jennifer R. Wortman,Jennifer R. Wortman,Martin Wu,Alison Yao,Evgeny M. Zdobnov,Hongyu Zhang,Qi Zhao,Shaying Zhao,Shiaoping C. Zhu,Igor F. Zhimulev,Mario Coluzzi,Alessandra della Torre,Charles Roth,Christos Louis,Francis Kalush,Richard J. Mural,Eugene W. Myers,Mark Raymond Adams,Hamilton O. Smith,Samuel Broder,Malcolm J. Gardner,Claire M. Fraser,Ewan Birney,Peer Bork,Paul T. Brey,J. Craig Venter,J. Craig Venter,Jean Weissenbach,Fotis C. Kafatos,Frank H. Collins,Stephen L. Hoffman +126 more
TL;DR: Analysis of the PEST strain of A. gambiae revealed strong evidence for about 14,000 protein-encoding transcripts, and prominent expansions in specific families of proteins likely involved in cell adhesion and immunity were noted.
Journal ArticleDOI
Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae.
Dana Thomasova,Lucas Q. Ton,Richard R. Copley,Evgeny M. Zdobnov,X. Wang,Young S. Hong,Cheolho Sim,Peer Bork,Fotis C. Kafatos,Frank H. Collins +9 more
TL;DR: This sequence represents the first extensive view of the mosquito genome structure encompassing 48 genes and demonstrates the existence of a remarkable degree of local polymorphism in this species, which may prove important for its population structure and vectorial capacity.
Journal ArticleDOI
Genomic Analysis in the sting-2 Quantitative Trait Locus for Defensive Behavior in the Honey Bee, Apis mellifera
Neil F. Lobo,Lucas Q. Ton,Catherine A. Hill,Christine Emore,Jeanne Romero-Severson,Greg J. Hunt,Frank H. Collins +6 more
TL;DR: An 81-kb genomic region from the honey bee associated with a quantitative trait locus (QTL) sting-2 for aggressive behavior is sequenced, representing the first extensive study of the honey-bee genome structure encompassing putative genes in a QTL for a behavioral trait.
Journal ArticleDOI
On Methods of Germ-line Transformation and RNA Interference in African Malaria Mosquito, Anopheles gambiae
TL;DR: The technical details of Germ-line transformation and double-stranded RNAi should be useful to elucidate biological functions of those conceptually predicted genes in the A. gambiae genome as suggested in other organisms such as Caenorhabditis elegans and Drosophila melanogaster.