Jeffrey Hoover

TL;DR: Comparative genomic analysis indicates vertebrate expansions of genes associated with neuronal function, with tissue-specific developmental regulation, and with the hemostasis and immune systems are indicated.

TL;DR: Analysis of the PEST strain of A. gambiae revealed strong evidence for about 14,000 protein-encoding transcripts, and prominent expansions in specific families of proteins likely involved in cell adhesion and immunity were noted.

TL;DR: Comparative genomic analysis indicates vertebrate expansions of genes associated with neuronal function, with tissue-specific developmental regulation, and with the hemostasis and immune systems are indicated.

TL;DR: A chemical structure search system and method which capitalizes on the strengths of relational database technology, by allowing a user to optimally store and search chemical structure information, including information related to multivalued atoms, multi-typed bonds, and Markush searching, is presented in this article.

TL;DR: The approach combines the mutual selection of the best tBlastX hits between human and mouse transcripts, and inferring gene orthologous relationships based on sharing syntenic anchors, collocating in the same syntenic blocks and sharing the same annotated protein function, which resulted in a 20% increase in the number of orthologs identified by conventional approaches.