L
Lukas Lomb
Researcher at Max Planck Society
Publications - 39
Citations - 6543
Lukas Lomb is an academic researcher from Max Planck Society. The author has contributed to research in topics: Femtosecond & Diffraction. The author has an hindex of 25, co-authored 39 publications receiving 6055 citations.
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Journal ArticleDOI
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements
Anton Barty,Carl Caleman,Andrew Aquila,Nicusor Timneanu,Lukas Lomb,Thomas A. White,Jakob Andreasson,David Arnlund,Saša Bajt,Thomas R. M. Barends,Miriam Barthelmess,Michael J. Bogan,Christoph Bostedt,John D. Bozek,Ryan Coffee,Nicola Coppola,Jan Davidsson,Daniel P. DePonte,R. Bruce Doak,Tomas Ekeberg,Veit Elser,Sascha W. Epp,Benjamin Erk,Holger Fleckenstein,Lutz Foucar,Petra Fromme,Heinz Graafsma,Lars Gumprecht,Janos Hajdu,Christina Y. Hampton,Robert Hartmann,Andreas Hartmann,Günter Hauser,Helmut Hirsemann,Peter Holl,Mark S. Hunter,Linda C. Johansson,Stephan Kassemeyer,Nils Kimmel,Richard A. Kirian,Mengning Liang,Filipe R. N. C. Maia,Erik Malmerberg,Stefano Marchesini,Andrew V. Martin,Karol Nass,Richard Neutze,Christian Reich,Daniel Rolles,Benedikt Rudek,Artem Rudenko,Howard A. Scott,Ilme Schlichting,Joachim Schulz,M. Marvin Seibert,M. Marvin Seibert,Robert L. Shoeman,Raymond G. Sierra,Heike Soltau,John C. H. Spence,Francesco Stellato,Stephan Stern,Lothar Strüder,Joachim Ullrich,Xiaoyu Wang,Georg Weidenspointner,Uwe Weierstall,Cornelia B. Wunderer,Henry N. Chapman +68 more
TL;DR: Measurements indicate that current X-ray free-electron laser technology should enable structural determination from submicrometre protein crystals with atomic resolution, and the shortest apparent pulse lengths occur at the highest resolution.
Journal ArticleDOI
Time-resolved protein nanocrystallography using an X-ray free-electron laser
Andrew Aquila,Mark S. Hunter,R. Bruce Doak,Richard A. Kirian,Petra Fromme,Thomas A. White,Jakob Andreasson,David Arnlund,Saša Bajt,Thomas R. M. Barends,Miriam Barthelmess,Michael J. Bogan,Christoph Bostedt,Hervé Bottin,John D. Bozek,Carl Caleman,Nicola Coppola,Jan Davidsson,Daniel P. DePonte,Veit Elser,Sascha W. Epp,Benjamin Erk,Holger Fleckenstein,Lutz Foucar,Matthias Frank,Raimund Fromme,Heinz Graafsma,Ingo Grotjohann,Lars Gumprecht,Janos Hajdu,Christina Y. Hampton,Andreas Hartmann,Robert Hartmann,Stefan P. Hau-Riege,Günter Hauser,Helmut Hirsemann,Peter Holl,James M. Holton,André Hömke,Linda C. Johansson,Nils Kimmel,Stephan Kassemeyer,Faton Krasniqi,Kai Uwe Kuhnel,Mengning Liang,Lukas Lomb,Erik Malmerberg,Stefano Marchesini,Andrew V. Martin,Filipe R. N. C. Maia,Marc Messerschmidt,Karol Nass,Christian Reich,Richard Neutze,Daniel Rolles,Benedikt Rudek,Artem Rudenko,Ilme Schlichting,Carlo Schmidt,Kevin Schmidt,Joachim Schulz,M. Marvin Seibert,Robert L. Shoeman,Raymond G. Sierra,Heike Soltau,D. Starodub,Francesco Stellato,Stephan Stern,Lothar Strüder,Nicusor Timneanu,Joachim Ullrich,Xiaoyu Wang,Garth J. Williams,Georg Weidenspointner,Uwe Weierstall,Cornelia B. Wunderer,Anton Barty,John C. H. Spence,Henry N. Chapman +78 more
TL;DR: The first time-resolved femtosecond serial X-ray crystallography results from an irreversible photo-chemical reaction at the Linac Coherent Light Source are obtained.
Journal ArticleDOI
In vivo protein crystallization opens new routes in structural biology
Rudolf Koopmann,Karolina Cupelli,Lars Redecke,Karol Nass,Daniel P. DePonte,Thomas A. White,Francesco Stellato,Dirk Rehders,Mengning Liang,Jakob Andreasson,Andrew Aquila,Saša Bajt,Miriam Barthelmess,Anton Barty,Michael J. Bogan,Christoph Bostedt,Sébastien Boutet,John D. Bozek,Carl Caleman,Nicola Coppola,Jan Davidsson,R. Bruce Doak,Tomas Ekeberg,Sascha W. Epp,Benjamin Erk,Holger Fleckenstein,Lutz Foucar,Heinz Graafsma,Lars Gumprecht,Janos Hajdu,Janos Hajdu,Christina Y. Hampton,Andreas Hartmann,Robert Hartmann,Günter Hauser,Helmut Hirsemann,Peter Holl,Mark S. Hunter,Stephan Kassemeyer,Richard A. Kirian,Lukas Lomb,Filipe R. N. C. Maia,Nils Kimmel,Andrew V. Martin,Marc Messerschmidt,Christian Reich,Daniel Rolles,Benedikt Rudek,Artem Rudenko,Ilme Schlichting,Joachim Schulz,M. Marvin Seibert,M. Marvin Seibert,Robert L. Shoeman,Raymond G. Sierra,Heike Soltau,Stephan Stern,Lothar Strüder,Nicusor Timneanu,Joachim Ullrich,Xiaoyu Wang,Georg Weidenspointner,Uwe Weierstall,Garth J. Williams,Cornelia B. Wunderer,Petra Fromme,John C. H. Spence,Thilo Stehle,Thilo Stehle,Henry N. Chapman,Christian Betzel,Michael Duszenko +71 more
TL;DR: N nano-sized in vivo–grown crystals of Trypanosoma brucei enzymes are prepared and the emerging method of free-electron laser-based serial femtosecond crystallography is applied to record interpretable diffraction data to open new opportunities in structural systems biology.
Journal ArticleDOI
Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight
N. D. Loh,Christina Y. Hampton,Andrew V. Martin,Dmitri Starodub,Raymond G. Sierra,Anton Barty,Andrew Aquila,Joachim Schulz,Lukas Lomb,Jan Steinbrener,Robert L. Shoeman,Stephan Kassemeyer,Christoph Bostedt,John D. Bozek,Sascha W. Epp,Benjamin Erk,Raimo Hartmann,Daniel Rolles,Artem Rudenko,Benedikt Rudek,Lutz Foucar,Nils Kimmel,Georg Weidenspointner,Günter Hauser,Peter Holl,Emanuele Pedersoli,Mengning Liang,M. M. Hunter,Lars Gumprecht,Nicola Coppola,Cornelia B. Wunderer,H. Graafsma,Filipe R. N. C. Maia,Tomas Ekeberg,Max F. Hantke,H. Fleckenstein,Helmut Hirsemann,Karol Nass,Thomas A. White,Herbert J. Tobias,George R. Farquar,W. H. Benner,Stefan P. Hau-Riege,Christian Reich,Andreas Hartmann,Heike Soltau,Stefano Marchesini,Saša Bajt,Miriam Barthelmess,Philip H. Bucksbaum,Keith O. Hodgson,Lothar Strüder,Joachim Ullrich,Matthias Frank,Ilme Schlichting,Henry N. Chapman,Michael J. Bogan +56 more
TL;DR: In this article, an in situ method for imaging individual sub-micrometre-sized particles to nanometre resolution in flight using intense X-ray pulses from the Linac Coherent Light Source free-electron laser is presented.
Journal ArticleDOI
Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser
Lukas Lomb,Thomas R. M. Barends,Stephan Kassemeyer,Andrew Aquila,Sascha W. Epp,Benjamin Erk,Lutz Foucar,Robert Hartmann,Benedikt Rudek,Daniel Rolles,Artem Rudenko,Robert L. Shoeman,Jakob Andreasson,Saša Bajt,Miriam Barthelmess,Anton Barty,Michael J. Bogan,Christoph Bostedt,John D. Bozek,Carl Caleman,Ryan Coffee,Nicola Coppola,Daniel P. DePonte,R. Bruce Doak,Tomas Ekeberg,Holger Fleckenstein,Petra Fromme,Maike Gebhardt,Heinz Graafsma,Lars Gumprecht,Christina Y. Hampton,Andreas Hartmann,Guenter Hauser,Helmut Hirsemann,Peter Holl,James M. Holton,Mark S. Hunter,Wolfgang Kabsch,Nils Kimmel,Richard A. Kirian,Mengning Liang,Filipe R. N. C. Maia,Filipe R. N. C. Maia,Anton Meinhart,Stefano Marchesini,Andrew V. Martin,Karol Nass,Christian Reich,Joachim Schulz,M. Marvin Seibert,M. Marvin Seibert,Raymond G. Sierra,Heike Soltau,John C. H. Spence,Jan Steinbrener,Francesco Stellato,Stephan Stern,Nicusor Timneanu,Xiaoyu Wang,Georg Weidenspointner,Uwe Weierstall,Thomas A. White,Cornelia B. Wunderer,Henry N. Chapman,Joachim Ullrich,Lothar Strüder,Ilme Schlichting +66 more
TL;DR: Diffraction intensities of lysozyme nanocrystals collected at the Linac Coherent Light Source using 2 keV photons were used for structure determination by molecular replacement and analyzed for radiation damage as a function of pulse length and fluence.