H
Holger Fleckenstein
Researcher at Stony Brook University
Publications - 46
Citations - 4357
Holger Fleckenstein is an academic researcher from Stony Brook University. The author has contributed to research in topics: Femtosecond & Laser. The author has an hindex of 19, co-authored 39 publications receiving 3851 citations. Previous affiliations of Holger Fleckenstein include State University of New York System.
Papers
More filters
Journal ArticleDOI
Comet 81P/Wild 2 under a microscope.
Donald E. Brownlee,Peter Tsou,Jérôme Aléon,Conel M. O'd. Alexander,Tohru Araki,Saša Bajt,G. A. Baratta,Ron K. Bastien,Phil Bland,Phil Bland,Pierre Bleuet,Janet Borg,John P. Bradley,Adrian J. Brearley,Frank E. Brenker,Sean Brennan,John Bridges,Nigel D. Browning,Nigel D. Browning,John Robert Brucato,Emma S. Bullock,Mark J. Burchell,Henner Busemann,Anna L. Butterworth,Marc Chaussidon,Allan Cheuvront,Miaofang Chi,Mark J. Cintala,Benton C. Clark,Simon J. Clemett,George D. Cody,Luigi Colangeli,George Cooper,Patrick Cordier,Charles P. Daghlian,Zu Rong Dai,Louis Le Sergeant d'Hendecourt,Zahia Djouadi,Gerardo Dominguez,Tom Duxbury,Jason P. Dworkin,Denton S. Ebel,Thanasis E. Economou,Sirine C. Fakra,Sam A. J. Fairey,Stewart Fallon,G. Ferrini,T. Ferroir,Holger Fleckenstein,Christine Floss,George J. Flynn,Ian A. Franchi,Marc Fries,Zack Gainsforth,J-P Gallien,M. J. Genge,Mary K. Gilles,Philipe Gillet,Jamie Gilmour,Daniel P. Glavin,Matthieu Gounelle,Monica M. Grady,Giles A. Graham,Patrick G. Grant,Simon F. Green,F. Grossemy,Lawrence Grossman,Jeffrey N. Grossman,Yunbin Guan,Kenji Hagiya,Ralph P. Harvey,Philipp R. Heck,Gregory F. Herzog,Peter Hoppe,Friedrich Hörz,Joachim Huth,Ian D. Hutcheon,Konstantin Ignatyev,Hope A. Ishii,Motoo Ito,Damien Jacob,Chris Jacobsen,Stein B. Jacobsen,Steven Jones,David J. Joswiak,A. J. G. Jurewicz,Anton T. Kearsley,Lindsay P. Keller,H Khodja,A. L. David Kilcoyne,Jochen Kissel,Alexander N. Krot,Falko Langenhorst,Antonio Lanzirotti,Loan Le,Laurie A. Leshin,Jan Leitner,Laurence Lemelle,Hugues Leroux,Ming-Chang Liu,K. Luening,Ian C. Lyon,G. J. MacPherson,Matthew A. Marcus,Kuljeet K. Marhas,Bernard Marty,Graciela Matrajt,Kevin D. McKeegan,Anders Meibom,Vito Mennella,Keiko Messenger,Scott Messenger,Takashi Mikouchi,Smail Mostefaoui,Tomoki Nakamura,T Nakano,Matthew Newville,Larry R. Nittler,Ichiro Ohnishi,Kazumasa Ohsumi,Kyoko Okudaira,D. A. Papanastassiou,Russ Palma,Russ Palma,Maria Elisabetta Palumbo,Robert O. Pepin,David Perkins,Murielle C. Perronnet,Piero Pianetta,William Rao,Frans J. M. Rietmeijer,François Robert,Detlef Rost,Alessandra Rotundi,R. E. Ryan,Scott A. Sandford,Craig S. Schwandt,Thomas H. See,D. J. Schlutter,J. Sheffield-Parker,Alexandre Simionovici,Steven B. Simon,I Sitnitsky,Christopher J. Snead,Maegan K. Spencer,Frank J. Stadermann,Andrew Steele,Thomas Stephan,Rhonda M. Stroud,Jean Susini,Stephen R. Sutton,Y Suzuki,Mitra L. Taheri,Susan Taylor,Nick Teslich,Kazu Tomeoka,Naotaka Tomioka,Alice Toppani,Josep M. Trigo-Rodríguez,David Troadec,Akira Tsuchiyama,Anthony J. Tuzzolino,Tolek Tyliszczak,Kentaro Uesugi,Michael A. Velbel,Joe Vellenga,Edward P. Vicenzi,Laszlo Vincze,J. Warren,Iris Weber,M. K. Weisberg,Andrew J. Westphal,Sue Wirick,Diane H. Wooden,Brigitte Wopenka,Penelope J. Wozniakiewicz,Ian Wright,Hikaru Yabuta,Hajime Yano,Edward D. Young,Richard N. Zare,Thomas J. Zega,Karen Ziegler,Laurent Zimmerman,Ernst Zinner,Michael E. Zolensky +185 more
TL;DR: The Stardust spacecraft collected thousands of particles from comet 81P/Wild 2 and returned them to Earth for laboratory study, and preliminary examination shows that the nonvolatile portion of the comet is an unequilibrated assortment of materials that have both presolar and solar system origin.
Journal ArticleDOI
Organics captured from comet 81P/Wild 2 by the Stardust spacecraft.
Scott A. Sandford,Jérôme Aléon,Conel M. O'd. Alexander,Tohru Araki,Sašaǎ Bajt,G. A. Baratta,Janet Borg,John P. Bradley,Donald E. Brownlee,John Robert Brucato,Mark J. Burchell,Henner Busemann,Anna L. Butterworth,Simon J. Clemett,George D. Cody,Luigi Colangeli,George Cooper,Louis Le Sergeant d'Hendecourt,Zahia Djouadi,Jason P. Dworkin,G. Ferrini,Holger Fleckenstein,George J. Flynn,Ian A. Franchi,Marc Fries,Mary K. Gilles,Daniel P. Glavin,Matthieu Gounelle,F. Grossemy,Chris Jacobsen,Lindsay P. Keller,A. L. David Kilcoyne,Jan Leitner,Graciela Matrajt,Anders Meibom,Vito Mennella,Smail Mostefaoui,Larry R. Nittler,Maria Elisabetta Palumbo,D. A. Papanastassiou,François Robert,Alessandra Rotundi,Christopher J. Snead,Maegan K. Spencer,Frank J. Stadermann,Andrew Steele,Thomas Stephan,Peter Tsou,Tolek Tyliszczak,Andrew J. Westphal,Sue Wirick,Brigitte Wopenka,Hikaru Yabuta,Richard N. Zare,Michael E. Zolensky +54 more
TL;DR: The presence of deuterium and nitrogen-15 excesses suggest that some organics have an interstellar/protostellar heritage and a diverse suite of organic compounds is present and identifiable within the returned samples.
Journal ArticleDOI
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser
Lars Redecke,Lars Redecke,Karol Nass,Daniel P. DePonte,Thomas A. White,Dirk Rehders,Anton Barty,Francesco Stellato,Mengning Liang,Thomas R. M. Barends,Sébastien Boutet,Garth J. Williams,Marc Messerschmidt,M. Marvin Seibert,Andrew Aquila,David Arnlund,Saša Bajt,Torsten Barth,Michael J. Bogan,Carl Caleman,Tzu-Chiao Chao,R. Bruce Doak,Holger Fleckenstein,Matthias Frank,Raimund Fromme,Lorenzo Galli,Ingo Grotjohann,Mark S. Hunter,Linda C. Johansson,Stephan Kassemeyer,Gergely Katona,Richard A. Kirian,Rudolf Koopmann,Chris Kupitz,Lukas Lomb,Andrew V. Martin,Stefan Mogk,Richard Neutze,Robert L. Shoeman,Jan Steinbrener,Nicusor Timneanu,Dingjie Wang,Uwe Weierstall,Nadia A. Zatsepin,John C. H. Spence,Petra Fromme,Ilme Schlichting,Michael Duszenko,Christian Betzel,Henry N. Chapman +49 more
TL;DR: The structure reveals the mechanism of native TbCatB inhibition and demonstrates that new biomolecular information can be obtained by the “diffraction-before-destruction” approach of x-ray free-electron lasers from hundreds of thousands of individual microcrystals.
Journal ArticleDOI
Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Christopher Kupitz,Shibom Basu,Ingo Grotjohann,Raimund Fromme,Nadia A. Zatsepin,Kimberly N. Rendek,Mark S. Hunter,Mark S. Hunter,Robert L. Shoeman,Thomas A. White,Dingjie Wang,Daniel James,Jay-How Yang,Danielle E. Cobb,Brenda Reeder,Raymond G. Sierra,Haiguang Liu,Anton Barty,Andrew Aquila,Daniel P. DePonte,Richard A. Kirian,Sadia Bari,Jesse J. Bergkamp,Kenneth R. Beyerlein,Michael J. Bogan,Carl Caleman,Tzu-Chiao Chao,Tzu-Chiao Chao,Chelsie E. Conrad,Katherine M. Davis,Holger Fleckenstein,Lorenzo Galli,Stefan P. Hau-Riege,Stephan Kassemeyer,Hartawan Laksmono,Mengning Liang,Lukas Lomb,Stefano Marchesini,Andrew V. Martin,Marc Messerschmidt,Despina Milathianaki,Karol Nass,Alexandra Ros,Shatabdi Roy-Chowdhury,Kevin Schmidt,M. Marvin Seibert,M. Marvin Seibert,Jan Steinbrener,Francesco Stellato,Lifen Yan,Chun Hong Yoon,Thomas A. Moore,Ana L. Moore,Yulia Pushkar,Garth J. Williams,Sébastien Boutet,R. Bruce Doak,Uwe Weierstall,Matthias Frank,Henry N. Chapman,John C. H. Spence,Petra Fromme +61 more
TL;DR: Time resolved experiments on PSII nano/microcrystals from Thermosynechococcus elongatus performed with the recently developed technique of serial femtosecond crystallography provide evidence that PSII undergoes significant conformational changes at the electron acceptor side and at the Mn4CaO5 core of the OEC.
Journal ArticleDOI
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements
Anton Barty,Carl Caleman,Andrew Aquila,Nicusor Timneanu,Lukas Lomb,Thomas A. White,Jakob Andreasson,David Arnlund,Saša Bajt,Thomas R. M. Barends,Miriam Barthelmess,Michael J. Bogan,Christoph Bostedt,John D. Bozek,Ryan Coffee,Nicola Coppola,Jan Davidsson,Daniel P. DePonte,R. Bruce Doak,Tomas Ekeberg,Veit Elser,Sascha W. Epp,Benjamin Erk,Holger Fleckenstein,Lutz Foucar,Petra Fromme,Heinz Graafsma,Lars Gumprecht,Janos Hajdu,Christina Y. Hampton,Robert Hartmann,Andreas Hartmann,Günter Hauser,Helmut Hirsemann,Peter Holl,Mark S. Hunter,Linda C. Johansson,Stephan Kassemeyer,Nils Kimmel,Richard A. Kirian,Mengning Liang,Filipe R. N. C. Maia,Erik Malmerberg,Stefano Marchesini,Andrew V. Martin,Karol Nass,Richard Neutze,Christian Reich,Daniel Rolles,Benedikt Rudek,Artem Rudenko,Howard A. Scott,Ilme Schlichting,Joachim Schulz,M. Marvin Seibert,M. Marvin Seibert,Robert L. Shoeman,Raymond G. Sierra,Heike Soltau,John C. H. Spence,Francesco Stellato,Stephan Stern,Lothar Strüder,Joachim Ullrich,Xiaoyu Wang,Georg Weidenspointner,Uwe Weierstall,Cornelia B. Wunderer,Henry N. Chapman +68 more
TL;DR: Measurements indicate that current X-ray free-electron laser technology should enable structural determination from submicrometre protein crystals with atomic resolution, and the shortest apparent pulse lengths occur at the highest resolution.