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Stephan Kassemeyer
Researcher at Max Planck Society
Publications - 31
Citations - 3911
Stephan Kassemeyer is an academic researcher from Max Planck Society. The author has contributed to research in topics: Femtosecond & Laser. The author has an hindex of 20, co-authored 31 publications receiving 3633 citations.
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Journal ArticleDOI
High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography
Sébastien Boutet,Lukas Lomb,Garth J. Williams,Thomas R. M. Barends,Andrew Aquila,R. Bruce Doak,Uwe Weierstall,Daniel P. DePonte,Jan Steinbrener,Robert L. Shoeman,Marc Messerschmidt,Anton Barty,Thomas A. White,Stephan Kassemeyer,Richard A. Kirian,M. Marvin Seibert,Paul A. Montanez,C.J. Kenney,Ryan Herbst,P. Hart,J. Pines,Gunther Haller,Sol M. Gruner,Hugh T. Philipp,Mark W. Tate,Marianne Hromalik,Lucas J. Koerner,Niels van Bakel,John Morse,W. Ghonsalves,David Arnlund,Michael J. Bogan,Carl Caleman,Raimund Fromme,Christina Y. Hampton,Mark S. Hunter,Linda C. Johansson,Gergely Katona,Christopher Kupitz,Mengning Liang,Andrew V. Martin,Karol Nass,Lars Redecke,Lars Redecke,Francesco Stellato,Nicusor Timneanu,Dingjie Wang,Nadia A. Zatsepin,Donald W. Schafer,James Defever,Richard Neutze,Petra Fromme,John C. H. Spence,Henry N. Chapman,Ilme Schlichting +54 more
TL;DR: Serial femtosecond crystallography (SFX) is applied using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals of the well-characterized model protein lysozyme, demonstrating the immediate relevance of SFX for analyzing the structure of the large group of difficult-to-crystallize molecules.
Journal ArticleDOI
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser
Lars Redecke,Lars Redecke,Karol Nass,Daniel P. DePonte,Thomas A. White,Dirk Rehders,Anton Barty,Francesco Stellato,Mengning Liang,Thomas R. M. Barends,Sébastien Boutet,Garth J. Williams,Marc Messerschmidt,M. Marvin Seibert,Andrew Aquila,David Arnlund,Saša Bajt,Torsten Barth,Michael J. Bogan,Carl Caleman,Tzu-Chiao Chao,R. Bruce Doak,Holger Fleckenstein,Matthias Frank,Raimund Fromme,Lorenzo Galli,Ingo Grotjohann,Mark S. Hunter,Linda C. Johansson,Stephan Kassemeyer,Gergely Katona,Richard A. Kirian,Rudolf Koopmann,Chris Kupitz,Lukas Lomb,Andrew V. Martin,Stefan Mogk,Richard Neutze,Robert L. Shoeman,Jan Steinbrener,Nicusor Timneanu,Dingjie Wang,Uwe Weierstall,Nadia A. Zatsepin,John C. H. Spence,Petra Fromme,Ilme Schlichting,Michael Duszenko,Christian Betzel,Henry N. Chapman +49 more
TL;DR: The structure reveals the mechanism of native TbCatB inhibition and demonstrates that new biomolecular information can be obtained by the “diffraction-before-destruction” approach of x-ray free-electron lasers from hundreds of thousands of individual microcrystals.
Journal ArticleDOI
Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser.
Christopher Kupitz,Shibom Basu,Ingo Grotjohann,Raimund Fromme,Nadia A. Zatsepin,Kimberly N. Rendek,Mark S. Hunter,Mark S. Hunter,Robert L. Shoeman,Thomas A. White,Dingjie Wang,Daniel James,Jay-How Yang,Danielle E. Cobb,Brenda Reeder,Raymond G. Sierra,Haiguang Liu,Anton Barty,Andrew Aquila,Daniel P. DePonte,Richard A. Kirian,Sadia Bari,Jesse J. Bergkamp,Kenneth R. Beyerlein,Michael J. Bogan,Carl Caleman,Tzu-Chiao Chao,Tzu-Chiao Chao,Chelsie E. Conrad,Katherine M. Davis,Holger Fleckenstein,Lorenzo Galli,Stefan P. Hau-Riege,Stephan Kassemeyer,Hartawan Laksmono,Mengning Liang,Lukas Lomb,Stefano Marchesini,Andrew V. Martin,Marc Messerschmidt,Despina Milathianaki,Karol Nass,Alexandra Ros,Shatabdi Roy-Chowdhury,Kevin Schmidt,M. Marvin Seibert,M. Marvin Seibert,Jan Steinbrener,Francesco Stellato,Lifen Yan,Chun Hong Yoon,Thomas A. Moore,Ana L. Moore,Yulia Pushkar,Garth J. Williams,Sébastien Boutet,R. Bruce Doak,Uwe Weierstall,Matthias Frank,Henry N. Chapman,John C. H. Spence,Petra Fromme +61 more
TL;DR: Time resolved experiments on PSII nano/microcrystals from Thermosynechococcus elongatus performed with the recently developed technique of serial femtosecond crystallography provide evidence that PSII undergoes significant conformational changes at the electron acceptor side and at the Mn4CaO5 core of the OEC.
Journal ArticleDOI
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements
Anton Barty,Carl Caleman,Andrew Aquila,Nicusor Timneanu,Lukas Lomb,Thomas A. White,Jakob Andreasson,David Arnlund,Saša Bajt,Thomas R. M. Barends,Miriam Barthelmess,Michael J. Bogan,Christoph Bostedt,John D. Bozek,Ryan Coffee,Nicola Coppola,Jan Davidsson,Daniel P. DePonte,R. Bruce Doak,Tomas Ekeberg,Veit Elser,Sascha W. Epp,Benjamin Erk,Holger Fleckenstein,Lutz Foucar,Petra Fromme,Heinz Graafsma,Lars Gumprecht,Janos Hajdu,Christina Y. Hampton,Robert Hartmann,Andreas Hartmann,Günter Hauser,Helmut Hirsemann,Peter Holl,Mark S. Hunter,Linda C. Johansson,Stephan Kassemeyer,Nils Kimmel,Richard A. Kirian,Mengning Liang,Filipe R. N. C. Maia,Erik Malmerberg,Stefano Marchesini,Andrew V. Martin,Karol Nass,Richard Neutze,Christian Reich,Daniel Rolles,Benedikt Rudek,Artem Rudenko,Howard A. Scott,Ilme Schlichting,Joachim Schulz,M. Marvin Seibert,M. Marvin Seibert,Robert L. Shoeman,Raymond G. Sierra,Heike Soltau,John C. H. Spence,Francesco Stellato,Stephan Stern,Lothar Strüder,Joachim Ullrich,Xiaoyu Wang,Georg Weidenspointner,Uwe Weierstall,Cornelia B. Wunderer,Henry N. Chapman +68 more
TL;DR: Measurements indicate that current X-ray free-electron laser technology should enable structural determination from submicrometre protein crystals with atomic resolution, and the shortest apparent pulse lengths occur at the highest resolution.
Journal ArticleDOI
Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser
Xuanxuan Li,Chun Ya Chiu,Hsiang Ju Wang,Stephan Kassemeyer,Sabine Botha,Robert L. Shoeman,Robert M. Lawrence,Christopher Kupitz,Richard A. Kirian,Daniel James,Dingjie Wang,Garrett Nelson,Marc Messerschmidt,Sébastien Boutet,Garth J. Williams,Elisabeth Hartmann,Aliakbar Jafarpour,Lutz Foucar,Anton Barty,Henry N. Chapman,Mengning Liang,Andreas Menzel,Fenglin Wang,Shibom Basu,Raimund Fromme,R. Bruce Doak,Petra Fromme,Uwe Weierstall,Michael H. Huang,John C. H. Spence,Ilme Schlichting,Brenda G. Hogue,Haiguang Liu +32 more
TL;DR: This corrects the article DOI: 10.1038/s data.2017.48 to S data.48.