M
Maarten F. Bijlsma
Researcher at University of Amsterdam
Publications - 74
Citations - 4301
Maarten F. Bijlsma is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 26, co-authored 41 publications receiving 3549 citations. Previous affiliations of Maarten F. Bijlsma include University of California, Berkeley & University of Washington.
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Journal ArticleDOI
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway.
Wouter J. de Jonge,Esmerij P. van der Zanden,Maarten F. Bijlsma,David J van Westerloo,Roelof J. Bennink,Hans-Rudolf Berthoud,Satoshi Uematsu,Shizuo Akira,Rene M. van den Wijngaard,Guy E. Boeckxstaens +9 more
TL;DR: In a mouse model of intestinal manipulation, stimulation of the vagus nerve ameliorated surgery-induced inflammation and postoperative ileus by activating STAT3 in intestinal macrophages and it is concluded that the vagal anti-inflammatory pathway acts by α7 subunit–mediated Jak2-STAT3 activation.
Journal ArticleDOI
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
Felipe De Sousa E Melo,Xin Wang,Marnix Jansen,Evelyn Fessler,Anne Trinh,Laura P M H de Rooij,Joan H. de Jong,Onno J. de Boer,Ronald van Leersum,Maarten F. Bijlsma,Hans M. Rodermond,Maartje van der Heijden,Maartje van der Heijden,Carel J. M. van Noesel,Jurriaan B. Tuynman,Evelien Dekker,Florian Markowetz,Jan Paul Medema,Louis Vermeulen,Louis Vermeulen +19 more
TL;DR: This work demonstrates, using an unsupervised classification strategy involving over 1,100 individuals with colon cancer, that three main molecularly distinct subtypes can be recognized, and provides evidence that this subtype relates to sessile-serrated adenomas.
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Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2) : a multicentre, patient-blinded, randomised controlled phase 2/3 trial
Jony van Hilst,Thijs de Rooij,Koop Bosscha,David J. Brinkman,Susan van Dieren,Marcel G. W. Dijkgraaf,Michael F. Gerhards,Ignace H. J. T. de Hingh,Tom M. Karsten,D.J. Lips,D.J. Lips,Misha D. P. Luyer,Olivier R. Busch,Sebastiaan Festen,Marc G. Besselink,Hendrik A. Marsman,Thomas M. van Gulik,Dennis A. Wicherts,Wietse J. Eshuis,Luna A Stibbe,Els Jm Nieveen van Dijkum,Janine E Van Hooft,Paul Fockens,Hanneke W. M. van Laarhoven,Johanna W. Wilmink,Marcel J Van de Vijver,Maarten F. Bijlsma,Joanne Verheij,C. Yung Nio,Krijn P. van Lienden,Geertjan van Tienhoven,Annuska Schoorlemmer,Geert-Jan Creemers,Casper H.J. van Eijck,Bas Groot Koerkamp,Marco J. Bruno,Ferry A.L.M. Eskens,Joost J. Nuyttens,Chulja Pek,George P. van der Schelling,Tom C.J. Seerden,Gijs A. Patijn,Vincent B. Nieuwenhuijs,Jan Willem B. de Groot,Bert A. Bonsing,Alexander L. Vahrmeijer,R.-J. Swijnenburg,J. Sven D. Mieog,Erwin van der Harst,Matthijs Den Dulk,Steven W.M. Olde Damink,Cees H. Dejong,Ronald Van Dam,Judith Mpgm De Vos,Mike Sl Liem,Cees J. H. M. van Laarhoven,Harry van Goor,Peter B. van den Boezem,B. Marion van der Kolk,Martijn Wj Stommel,John J. Hermans,Erwin J M van Geenen,Sandra A Radema,Lodewijk A.A. Brosens,Joris J. Scheepers,Daphne Roos,Djamilla Boerma,Wouter W. te Riele,Hjalmar C. van Santvoort,Thomas L. Bollen,Fanny Wit,I. Quintus Molenaar,Nadia Haj Mohammad,Maarten S. van Leeuwen,Annemarie Roele,Kees P De Jong,Vincent E de Meijer,Joost M. Klaase,Geert Kazemier,Babs M Zonderhuis,Freek Daams,Martijn R. Meijerink,Anouk E J Latenstein,L. Bengt van Rijssen,Carolijn L.M.A. Nota,Emo Van Halsema,Eran van Veldhuisen,Jantien A. Vogel,Kiki Janssen,Lianne Scholten,Lois A. Daamen,Marieke S. Walma,Marin Strijker,Mariska Prins,Maurice J. W. Zwart,Mustafa Suker,Steffi J.E. Rombouts,Timothy H. Mungroop,F. Vissers,Maarten Korrel +99 more
TL;DR: This multicentre, patient-blinded, parallel-group, randomised controlled phase 2/3 trial was performed in four centres in the Netherlands to assess whether laparoscopic pancreatoduodenectomy could reduce time to functional recovery compared with open pancreatic fistula.
Journal ArticleDOI
Repression of Smoothened by Patched-Dependent (Pro-)Vitamin D3 Secretion
Maarten F. Bijlsma,C. Arnold Spek,Danica Zivkovic,Sandra van de Water,Farhad Rezaee,Maikel P. Peppelenbosch +5 more
TL;DR: Hh activates its signalling cascade by inhibiting Ptch1-dependent secretion of the 3β-hydroxysteroid (pro-)vitamin D3, which establishes Hh as a unique morphogen, because binding of Hh on one cell is capable of activating Hh-dependent signalling cascades on other cells.
Journal ArticleDOI
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer
Erica J. Childs,Evelina Mocci,Daniele Campa,Daniele Campa,Paige M. Bracci,Steven Gallinger,Michael Goggins,Donghui Li,Rachel E. Neale,Sara H. Olson,Ghislaine Scelo,Laufey T. Amundadottir,William R. Bamlet,Maarten F. Bijlsma,Amanda L. Blackford,Michael Borges,Paul Brennan,Hermann Brenner,H. Bas Bueno-de-Mesquita,Federico Canzian,Gabriele Capurso,Giulia Martina Cavestro,Kari G. Chaffee,Stephen J. Chanock,Sean P. Cleary,Michelle Cotterchio,Lenka Foretova,Charles S. Fuchs,Niccola Funel,Maria Gazouli,Manal M. Hassan,Joseph M. Herman,Ivana Holcatova,Elizabeth A. Holly,Robert N. Hoover,Rayjean J. Hung,Vladimir Janout,Timothy J. Key,Juozas Kupcinskas,Robert C. Kurtz,Stefano Landi,Lingeng Lu,Ewa Małecka-Panas,Andrea Mambrini,Beatrice Mohelnikova-Duchonova,John P. Neoptolemos,Ann L. Oberg,Irene Orlow,Claudio Pasquali,Raffaele Pezzilli,Cosmeri Rizzato,Amethyst Saldia,Aldo Scarpa,Rachael Z. Stolzenberg-Solomon,Oliver Strobel,Francesca Tavano,Yogesh K. Vashist,Pavel Vodicka,Brian M. Wolpin,Herbert Yu,Gloria M. Petersen,Harvey A. Risch,Alison P. Klein +62 more
TL;DR: This study identifies new loci associated with pancreatic cancer risk in North America, Central Europe and Australia and replicated previously reported associations at 9q34.2 (ABO), 13q22.1 (KLF5), 5p15.33 (TERT and CLPTM1) and 13q12.4 (NR5A2), a region with previous suggestive evidence in Han Chinese.