M
Marcin Wawrzyniak
Researcher at University of Zurich
Publications - 35
Citations - 2448
Marcin Wawrzyniak is an academic researcher from University of Zurich. The author has contributed to research in topics: Inflammation & Immune system. The author has an hindex of 17, co-authored 30 publications receiving 1676 citations. Previous affiliations of Marcin Wawrzyniak include Swiss Institute of Allergy and Asthma Research.
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Journal ArticleDOI
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases
Mübeccel Akdis,Alar Aab,Can Altunbulakli,Kursat A Azkur,Rita Costa,Reto Crameri,Su Duan,Thomas Eiwegger,Andrzej Eljaszewicz,Ruth Ferstl,Remo Frei,Mattia Garbani,Anna Głobińska,Lena Hess,Carly Huitema,Terufumi Kubo,Zsolt István Komlósi,Patricia Konieczna,Nóra Kovács,Umut Can Kucuksezer,Norbert Meyer,Hideaki Morita,Judith Olzhausen,Liam O'Mahony,Marija Pezer,Moira Prati,Ana Rebane,Claudio Rhyner,Arturo Rinaldi,Milena Sokolowska,Barbara Stanic,Kazunari Sugita,Angela Treis,Willem van de Veen,Kerstin Wanke,Marcin Wawrzyniak,Paulina Wawrzyniak,Oliver F. Wirz,Josefina Zakzuk,Cezmi A. Akdis +39 more
TL;DR: Recent developments on IL-1 to IL-38, TNF-α, TGF-β, and interferons are reviewed and their cellular sources, targets, receptors, signaling pathways, and roles in immune regulation in patients with allergy and asthma and other inflammatory diseases are discussed.
Journal ArticleDOI
IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses
Willem van de Veen,Barbara Stanic,Görkem Yaman,Marcin Wawrzyniak,Stefan Söllner,Deniz Akdis,Beate Rückert,Cezmi A. Akdis,Mübeccel Akdis +8 more
TL;DR: The characterization of IL-10+ BR1 cells and in vivo evidence for 2 essential features of allergen tolerance: the suppressive B cells and IgG4-expressing B cells that are confined to IL- 10+BR1 cells in human subjects are shown.
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High levels of butyrate and propionate in early life are associated with protection against atopy.
Caroline Roduit,Remo Frei,Ruth Ferstl,Susanne Loeliger,Patrick Westermann,Claudio Rhyner,Elisa Schiavi,Weronika Barcik,Noelia Rodriguez-Perez,Marcin Wawrzyniak,Christophe Chassard,Christophe Lacroix,Elisabeth Schmausser-Hechfellner,Martin Depner,Erika von Mutius,Charlotte Braun-Fahrländer,Charlotte Braun-Fahrländer,Anne M. Karvonen,Pirkka V. Kirjavainen,Pirkka V. Kirjavainen,Juha Pekkanen,Juha Pekkanen,Jean-Charles Dalphin,Josef Riedler,Cezmi A. Akdis,Roger Lauener,Liam O'Mahony,Liam O'Mahony +27 more
TL;DR: The potential role of SCFAs in the prevention of allergy and asthma was investigated in animal models and metabolites present in certain foods were investigated.
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Regulation of Bronchial Epithelial Barrier Integrity by Type 2 Cytokines and Histone Deacetylases in Asthmatic Patients
Paulina Wawrzyniak,Marcin Wawrzyniak,Kerstin Wanke,Milena Sokolowska,Krešo Bendelja,Beate Rückert,Anna Głobińska,Bogdan Jakiela,Jeannette I. Kast,Marco Idzko,Mübeccel Akdis,Marek Sanak,Cezmi A. Akdis +12 more
TL;DR: The data demonstrate that barrier leakiness in asthmatic patients is induced by TH2 cells, IL‐4, and IL‐13 and HDAC activity, which improved barrier integrity through increased synthesis of TJ molecules in epithelium from astHmatic patients to the level seen in HBECs from control subjects.
Journal ArticleDOI
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid.
Hideaki Morita,Terufumi Kubo,Beate Rückert,Avinash Ravindran,Michael B. Soyka,Arturo Rinaldi,Kazunari Sugita,Marcin Wawrzyniak,Paulina Wawrzyniak,Kenichiro Motomura,Masato Tamari,Keisuke Orimo,Naoko Okada,Ken Arae,Kyoko Saito,Can Altunbulakli,Francesc Castro-Giner,Francesc Castro-Giner,Ge Tan,Ge Tan,Avidan U. Neumann,Katsuko Sudo,Liam O'Mahony,Liam O'Mahony,Kenya Honda,Susumu Nakae,Susumu Nakae,Hirohisa Saito,Jenny Mjösberg,Gunnar Nilsson,Kenji Matsumoto,Mübeccel Akdis,Cezmi A. Akdis +32 more
TL;DR: A unique immune regulatory and anti-inflammatory pathway is identified by which RA converts ILC2s to ILCregs, which expresses a regulatory T cell-like signature with expression of IL-10, cytotoxic T lymphocyte-associated protein 4, and CD25.