Maria Calderon-Dominguez

TL;DR: Obesity is accompanied by an increase in BAT mitochondrial activity, inflammation and oxidative damage, which suggests that BAT is more resistant to the obesity-induced insult.

TL;DR: Enhanced FAO in palmitate-incubated adipocytes and macrophages reduced triglyceride content and inflammation, improved insulin sensitivity in adipocytes, and reduced endoplasmic reticulum stress and ROS damage in Macrophages indicates that enhancingFAO in metabolically relevant cells such as adipocyte andmacrophages may be a promising strategy for the treatment of chronic inflammatory pathologies such as obesity and type 2 diabetes.

TL;DR: This review highlights the mechanisms of fatty acid uptake, trafficking and oxidation in brown fat thermogenesis and focuses on BAT's morphological and functional characteristics and fatty acid synthesis, storage, oxidation and use as a source of energy.

TL;DR: In this article, the authors describe pathological processes associated with obesity that may influence the correct differentiation of BAT, such as catecholamine resistance, inflammation, oxidative stress, and endoplasmic reticulum stress.

TL;DR: There is a lack both in the amount and impact of research conducted in Latin America on vascular disorders related to problems during pregnancy, and the need for increased effective regional and international collaboration to generate new data specific to this region is related.