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Martha Sosa-Macías

Researcher at Instituto Politécnico Nacional

Publications -  54
Citations -  728

Martha Sosa-Macías is an academic researcher from Instituto Politécnico Nacional. The author has contributed to research in topics: Population & Allele frequency. The author has an hindex of 15, co-authored 47 publications receiving 585 citations.

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CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards.

TL;DR: The present data suggest the need for pharmacogenetic studies to optimize drug dosages in different populations, and add further evidence about CYP2C9 genetic diversity within Hispanic populations with regard to their ancestry.
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DNA and oxidative damages decrease after ingestion of folic acid in patients with type 2 diabetes.

TL;DR: A positive correlation exists between oxidative stress produced by Type 2 diabetes mellitus and DNA damage, so the use of an antioxidant such as folic acid in DM2 therapy is advisable for delaying complications due to T2DM-induced oxidative stress andDNA damage.
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Paternal Determinants in Preeclampsia.

TL;DR: The evidences of the father’s contribution to the onset of preeclampsia are evaluated and the importance of including them in future studies is determined to determine.
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CYP2D6 genotype and phenotype in Amerindians of Tepehuano origin and Mestizos of Durango, Mexico.

TL;DR: The Tepehuano population was found to have a low phenotypic and genotypic CYP2D6 diversity and differed from other Amerindian groups, while the frequencies of the CYP 2D6 variant alleles in Mestizos were similar to those reported for whites.