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Marie C. Béné

Researcher at University of Nantes

Publications -  329
Citations -  10251

Marie C. Béné is an academic researcher from University of Nantes. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 44, co-authored 273 publications receiving 8444 citations. Previous affiliations of Marie C. Béné include University of Toulouse & Paris Descartes University.

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Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study

TL;DR: D-VTd before and after autologous stem-cell transplantation improved depth of response and progression-free survival with acceptable safety and CASSIOPEIA is the first study showing the clinical benefit of daratumumab plus standard of care in transplant-eligible patients with newly diagnosed multiple myeloma.
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A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.

TL;DR: Both in vitro and in vivo, a synthetic peptide mimicking a short highly conserved domain of sTREM-1 appeared to attenuate cytokine production by human monocytes and protect septic animals from hyper-responsiveness and death.
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Plasma Level of a Triggering Receptor Expressed on Myeloid Cells-1: Its Diagnostic Accuracy in Patients with Suspected Sepsis

TL;DR: The diagnostic value of an assay measuring the plasma level of soluble TREM-1 in distinguishing sepsis from severe systemic noninfectious inflammation among newly admitted critically ill patients with suspected infection is prospectively investigated.