M
Mark D. Holton
Researcher at Swansea University
Publications - 66
Citations - 1376
Mark D. Holton is an academic researcher from Swansea University. The author has contributed to research in topics: Computer science & Animal ecology. The author has an hindex of 16, co-authored 61 publications receiving 1011 citations.
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Journal ArticleDOI
Statistical analysis of nanoparticle dosing in a dynamic cellular system
Huw D. Summers,Paul Rees,Mark D. Holton,M. Rowan Brown,Sally Claire Chappell,Paul J. Smith,Rachel J. Errington +6 more
TL;DR: The results show that cellular targeting of nanoparticles is inherently imprecise due to the randomness of nature at the molecular scale, and the statistical framework offers a way to predict nanoparticle dosage for therapy and for the study of nanotoxins.
Journal ArticleDOI
Estimates for energy expenditure in free-living animals using acceleration proxies: A reappraisal
Rory P. Wilson,Luca Börger,Mark D. Holton,D. Michael Scantlebury,Agustina Gómez-Laich,Flavio Quintana,Frank Rosell,Patricia Maria Graf,Patricia Maria Graf,Hannah J. Williams,Richard Gunner,Lloyd W. Hopkins,Nikki J. Marks,Nathan R. Geraldi,Carlos M. Duarte,Rebecca Scott,Michael S. Strano,Hermina Robotka,Christophe Eizaguirre,Andreas Fahlman,Emily L. C. Shepard,Emily L. C. Shepard +21 more
TL;DR: Overall, DBA seems to be a substantive proxy for movement-based power but consideration of other movement-related metrics, such as the Static Body Acceleration and the rate of change of body pitch and roll, may enable researchers to refine movement- based metabolic costs, particularly in animals where movement is not characterized by marked changes in body acceleration.
Journal ArticleDOI
Identification of animal movement patterns using tri-axial magnetometry
Hannah J. Williams,Mark D. Holton,Emily L. C. Shepard,Nicola Largey,Brad Norman,Peter G. Ryan,Olivier Duriez,Michael Scantlebury,Flavio Quintana,Elizabeth Magowan,Nikki J. Marks,Abdulaziz N. Alagaili,Nigel C. Bennett,Rory P. Wilson +13 more
TL;DR: Tri-axial magnetometry data reveal patterns in movement at various scales of rotation that are not always evident in acceleration data, and shows promise for helping researchers to identify and quantify behaviours in terms of animal body posture, including heading.
Journal ArticleDOI
Quantitative characterization of nanoparticle agglomeration within biological media
Nicole Hondow,Rik Brydson,Peiyi Wang,Mark D. Holton,M. Rowan Brown,Paul Rees,Huw D. Summers,Andy Brown +7 more
TL;DR: A comparative study of TEM and DLS is presented and it is shown that plunge-freeze TEM provides a robust assessment of nanoparticle agglomeration state.
Journal ArticleDOI
Identification of behaviours from accelerometer data in a wild social primate
Gaelle Fehlmann,M. Justin O'Riain,Phil W. Hopkins,Jack O’Sullivan,Mark D. Holton,Emily L. C. Shepard,Andrew J. King +6 more
TL;DR: The ‘end to end’ process—from collar design and build to the collection and quantification of acceleration data—provides advantages over gathering data by traditional observation, not least because it affords data collection without the presence of an observer which may affect an animal’s behaviour.