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Philip J. R. Day
Researcher at University of Manchester
Publications - 154
Citations - 6634
Philip J. R. Day is an academic researcher from University of Manchester. The author has contributed to research in topics: Ricin & Gene. The author has an hindex of 46, co-authored 153 publications receiving 6134 citations. Previous affiliations of Philip J. R. Day include University of Cape Town & University of Hong Kong.
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Journal ArticleDOI
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
TL;DR: Improving enzymes by directed evolution requires the navigation of very large search spaces; this work surveys how to do this intelligently.
Journal ArticleDOI
Exploring the role of stem cells in cutaneous wound healing.
TL;DR: A critical synthesis of the current understanding of the role of stem cells in normal cutaneous wound healing is presented and current strategies, future applications, and limitations of stem cell-based or stem cell‐targeted therapy in the management of acute and chronic skin wounds are delineated.
Journal ArticleDOI
The need for transparency and good practices in the qPCR literature
Stephen A. Bustin,Vladimir Benes,Jeremy A. Garson,Jan Hellemans,Jim F. Huggett,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Carl T. Wittwer,Peter Schjerling,Philip J. R. Day,Mónica Abreu,Begoña Aguado,Jean-François Beaulieu,Anneleen Beckers,Sara Bogaert,John A. Browne,Fernando Carrasco-Ramiro,Liesbeth Ceelen,Kate L. Ciborowski,Pieter Cornillie,Stephanie Coulon,Ann Cuypers,Sara De Brouwer,Leentje De Ceuninck,Jurgen De Craene,Hélène De Naeyer,Ward De Spiegelaere,Kato Deckers,Annelies Dheedene,Kaat Durinck,Margarida Ferreira-Teixeira,Annelies Fieuw,Jack M. Gallup,Sandra Gonzalo-Flores,Karen Goossens,Femke Heindryckx,Elizabeth Herring,Hans Hoenicka,Laura Icardi,Rolf Jaggi,Farzad Javad,Michael Karampelias,Frederick S. B. Kibenge,Molly J. T. Kibenge,Candy Kumps,Irina Lambertz,Tim Lammens,Amelia Markey,Peter Messiaen,Evelien Mets,Sofia Morais,Alberto Mudarra-Rubio,Justine K. Nakiwala,Hilde Nelis,Pål A. Olsvik,Claudina Perez-Novo,Michelle Plusquin,Tony Remans,Ali Rihani,Paulo Rodrigues-Santos,Pieter Rondou,Rebecca Sanders,Katharina Schmidt-Bleek,Kerstin Skovgaard,Karen Smeets,Laura Tabera,Stefan Toegel,Tim Van Acker,Wim Van den Broeck,Joni Van der Meulen,Mireille Van Gele,Gert Van Peer,Mario Van Poucke,Nadine Van Roy,Sarah Vergult,Joris Wauman,Marina Tshuikina-Wiklander,Erik Willems,Sara Zaccara,Fjoralba Zeka,Jo Vandesompele +83 more
TL;DR: Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information.
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A radiation hybrid map of the rat genome containing 5,255 markers.
Takeshi K. Watanabe,M. T. Bihoreau,Linda McCarthy,Susanna L. Kiguwa,Haretsugu Hishigaki,Atsushi B. Tsuji,Julie Browne,Yuki Yamasaki,Ayako Mizoguchi-Miyakita,Keiko Oga,Toshihide Ono,Shiro Okuno,Naohide Kanemoto,Ei Ichi Takahashi,Kazuhiro Tomita,Hiromi Hayashi,Masakazu Adachi,Caleb Webber,Marie Davis,Susanne Kiel,Catherine Knights,Angela L. Smith,Ricky Critcher,Jonathan Miller,Thiru Thangarajah,Philip J. R. Day,James R. Hudson,Yasuo Irie,Toshihisa Takagi,Yusuke Nakamura,Peter N. Goodfellow,G. Mark Lathrop,Akira Tanigami,Michael R. James +33 more
TL;DR: A whole-genome radiation hybrid panel was used to construct a high-resolution map of the rat genome based on microsatellite and gene markers, described here for the first time, allowing the construction of detailed rat-mouse and rat-human comparative maps and illustrating the power of the RH approach for comparative mapping.
Journal ArticleDOI
Miniaturised nucleic acid analysis
TL;DR: The primary focus of this review is to detail recent new approaches to sample preparation, nucleic acid amplification and detection within microfluidic devices or at the microscale level.